[1]王雪菲,王杰,沈红权.基于数据挖掘探讨中药内服治疗糖尿病周围神经病变的用药规律[J].西部中医药,2025,38(01):94-98.[doi:10.12174/j.issn.2096-9600.2025.01.18]
　WANG Xuefei,WANG Jie,SHEN Hongquan.Medication Rule of Herbal Administration in the Treatment of Diabetic Peripheral Neuropathy Based on Data Mining[J].Western Journal of Traditional Chinese Medicine,2025,38(01):94-98.[doi:10.12174/j.issn.2096-9600.2025.01.18]
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基于数据挖掘探讨中药内服治疗糖尿病周围神经病变的用药规律()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
38
期数:
2025年01期
页码:
94-98
栏目:
二次研究
出版日期:
2025-01-15

文章信息/Info

Title:
Medication Rule of Herbal Administration in the Treatment of Diabetic Peripheral Neuropathy Based on Data Mining
作者:
王雪菲1, 王杰2, 沈红权2
1.上海中医药大学附属市中医医院,上海 200071
2.上海中医药大学附属普陀医院,上海 200062
Author(s):
WANG Xuefei1, WANG Jie2, SHEN Hongquan2
1.Shanghai City Hospital of Traditional Chinese Medicine, Shanghai 200071, China
2.Putuo Hospital Affiliated to Shanghai University of Traditional Chinese Medicine, Shanghai 200062, China
关键词:
糖尿病周围神经病变; 数据挖掘; 中医药; 用药规律
Keywords:
diabetic peripheral neuropathy; data mining; traditional Chinese medicine; medication rule
分类号:
R255.4
DOI:
10.12174/j.issn.2096-9600.2025.01.18
文献标志码:
A
摘要:
目的采用数据挖掘方法分析中药内服治疗糖尿病周围神经病变（diabetic peripheral neuropathy，DPN）的用药规律。 方法检索2013年1月至2022年12月CNKI、万方、维普、CBM数据库中公开发表的中药内服治疗DPN的方药，使用SPSS 25.0与IBM SPSS Modeler 18.0软件，利用频次统计、关联规则和系统聚类等方法分析用药规律。 结果共筛选得到中药内服处方136首，涉及中药151味，其中高频中药为当归、黄芪、川芎、鸡血藤等；常用药对为黄芪-鸡血藤、黄芪-地龙、黄芪-丹参、红花-桃仁等，聚类分析主要得出活血化瘀类、补气健脾类、补血养血类、养阴清热类4类药物。 结论中药内服治疗DPN以“益气养阴、活血化瘀”为基本大法，辅以清热、通络，桃红四物汤、黄芪桂枝五物汤、补阳还五汤、四君子汤、玉液汤加减为其核心处方。
Abstract:
ObjectiveTo analyze the medication rules of herbal administration in the treatment of diabetic peripheral neuropathy (DPN) using data mining method. MethodsThe published prescriptions on oral herbs in the treatment of DPN were retrieved from CNKI, Wanfang, VIP and CBM between January, 2013 and December 2022, SPSS 25.0 and IBM SPSS Modeler 18.0 software were applied to analyze the medication rules using frequency statistics, association rules and systematic clustering. ResultsThe study has gained 136 oral prescrip-tions, involving 151 herbs, among them, high-frequency herbs contained Danggui (Angelicae sinensis radix), Huangqi (Astragali radix), Chuanxiong (Chuanxiong rhizoma) and Jixueteng (Spatholobi Caulis); the commonly-used drug pairs were Huangqi-Jixueteng, Huangqi-Dilong (pheretima), Huangqi-Danshen (Salviae miltiorrhizae radix et rhizoma), Honghua (Carthami flos)-Taoren (Persicae semen), cluster analysis yielded four classes of drugs such as the drugs of blood-activating stasis-resolving, tonifying Qi and invigorating spleen, benefiting and nouri-shing blood, nourishing Yin and clearing heat. ConclusionOral administration of herbs in the treatment of DPN adopts "benefiting Qi and nourishing Yin, activating blood and resolving stasis" as the basic method, comple-menting clearing heat and dredging collaterals, with modified Taohong Siwu Tang, Huangqi Guizhi Wuwu Tang, Buyang Huanwu Tang, Sijunzi Tang and Yuye Tang as the core prescriptions.

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备注/Memo

备注/Memo:
王雪菲（1990—），女，硕士学位，主治医师。研究方向：内分泌代谢疾病的中西医结合治疗。国家自然科学基金（81973625）；上海中医药大学预算内科研项目（2021WK120）；沈红权上海市名老中医学术经验研究工作室（SHGZS-202224）；上海市中医医院第三届中医传承人才项目［SZYCC（2023-2024）-ZYCCXM03］。
更新日期/Last Update: 2025-01-15