[1]虞娟,李欣,曾玲玲.化癥消积汤联合TACE治疗原发性肝癌湿热毒蕴证疗效分析[J].西部中医药,2026,39(04):117-120.[doi:10.12174/j.issn.2096-9600.2026.04.25]
　YU Juan,LI Xin,ZENG Lingling.Analysis of Clinical Effectiveness of Masses-resolving and Accumulation-dispelling Decoction Joined with TACE in Treating Primary Liver Cancer with Accumulated Dampness, Heat, Toxin Pattern[J].Western Journal of Traditional Chinese Medicine,2026,39(04):117-120.[doi:10.12174/j.issn.2096-9600.2026.04.25]
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化癥消积汤联合TACE治疗原发性肝癌湿热毒蕴证疗效分析()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
39
期数:
2026年04期
页码:
117-120
栏目:
衷中参西
出版日期:
2026-04-15

文章信息/Info

Title:
Analysis of Clinical Effectiveness of Masses-resolving and Accumulation-dispelling Decoction Joined with TACE in Treating Primary Liver Cancer with Accumulated Dampness, Heat, Toxin Pattern
作者:
虞娟, 李欣, 曾玲玲
南通大学附属南京江北医院，江苏 南京 210048
Author(s):
YU Juan, LI Xin, ZENG Lingling
Nanjing Jiangbei Hospital Affiliated to Nantong University, Nanjing 210048, China
关键词:
肝癌; 化癥消积汤; 湿热毒蕴证; 生活质量
Keywords:
liver cancer; masses-resolving and accumulation-dispelling decoction; accumulated dampness;  heat;  toxin pattern; quality of life
分类号:
R273.5
DOI:
10.12174/j.issn.2096-9600.2026.04.25
文献标志码:
B
摘要:
目的分析化癥消积汤联合肝动脉化疗栓塞术（transarterial chemoembolization，TACE）治疗原发性肝癌（primary liver cancer，PLC）湿热毒蕴证患者的疗效。 方法收集PLC湿热毒蕴证患者72例，参考随机数字表法分为对照组与观察组，每组36例。两组患者采取经导管TACE治疗1个周期；对照组术后予常规保肝、护胃等措施；观察组术后采取与对照组相同治疗措施，并内服化癥消积汤。两组连续治疗12周。比较两组临床疗效及治疗前后肝功能、湿热毒蕴证评分、生活质量评分的变化情况。 结果连续治疗12周后，观察组总有效率［72.22%（26/36）］高于对照组［44.44%（16/36）］（P＜0.05）；两组谷草转氨酶（aspartate aminotransferase，AST）、谷丙转氨酶（alanine aminotransferase，ALT）、总胆红素（total bilirubin，TBIL）均降低，且观察组较对照组降低更显著（P＜0.05）；观察组湿热毒蕴证评分降低、卡氏评分均升高（P＜0.05），且观察组较对照组改善更显著（P＜0.05）。 结论化癥消积汤联合TACE治疗PLC湿热毒蕴证疗效明显，能改善患者的肝功能，减轻临床症状，提高生活质量。
Abstract:
ObjectiveTo analyze curative effects of masses-resolving and accumulation-dispelling decoction and TACE in treating primary liver cancer (PLC) with accumulated dampness, heat, toxin pattern. MethodsA total of 72 PLC patients were collected, and divided into the control group and the observation group according to random number table method with 36 cases in each. TACE was administered to the two groups for one therapeutic course; the control group accepted conventional measures of protecting liver and stomach after the operation, while the observation group adopted the same therapeutic measures as the control group, and took masses-resolving and accumulation-dispelling decoction orally. Both groups were treated for 12 weeks continuously. To compare clinical effects, liver function before and after the treatment, the scores of accumulated dampness, heat, toxin pattern, the scales of quality of life between the two groups. ResultsAfter 12 weeks of the treatment in a row, total effective rate of the observation group was [72.22%(26/36)], higher than [44.44%(16/36)] of the control group (P<0.05); the reduction in AST, ALT and TBIL was seen in the two groups, and the decrease of the observation group was more evident than that of the control group (P<0.05); the scores of accumulated dampness, heat, toxin pattern were lowered while Karnofsky score were lifted in the observation group (P<0.05), and the improvement of the observation group was more significant than that of the control group (P<0.05). ConclusionMasses-resolving and accumulation-dispelling decoction combined with TACE demonstrated noticeable clinical effects in treating PLC with accumulated dampness, heat, toxin pattern, it could improve liver function, relieve clinical symptoms and enhance quality of life.

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备注/Memo

备注/Memo:
国家自然科学基金面上项目（81774871）。虞娟（1988—），女，主治中医师。研究方向：肿瘤疾病的中医药诊治。Email：904391819@qq.com。
更新日期/Last Update: 2026-04-15