[1]王晓怀,寇嘉宁,潘文,等.黄芪注射液治疗脑梗死的Meta分析[J].西部中医药,2014,27(10):67.
点击复制

黄芪注射液治疗脑梗死的Meta分析
分享到:

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年10期
页码:
67
栏目:
专题·循证医学
出版日期:
2014-10-15

文章信息/Info

作者:
王晓怀12寇嘉宁34潘文2柳树英2
1 甘肃省中医院,甘肃 兰州 730050; 2 甘肃省中医药研究院; 3 复旦大学公共卫生学院; 4 上海市计划生育科学研究所
关键词:
黄芪注射液脑梗死系统评价
摘要:
目的:评价黄芪注射液治疗脑梗死的疗效与安全性。方法:计算机检索MEDLINE、EMbase、Cochrane图书馆、CNKI、VIP和万方数据库,按照纳入与排除标准由两位研究者独立筛选和提取资料,采用Cochrane协作网随机对照试验的质量评价标准评价纳入文献质量,使用Rev Man 5.2软件进行Meta分析。结果;共纳入10篇文献,864例患者。10篇文献报道均未见患者死亡情况,其病死率为0%。Meta分析结果显示:黄芪注射液组的临床疗效[RR=1.21,95%CI(1.13,1.29)]和神经功能缺损改善情况[MD=-3.28,95%CI(-5.27,-1.29)]均优于对照组,2组相比差异有统计学意义。纳入的10篇文献中,4篇文献报道未见明显不良反应,3篇未提及安全性或不良反应,2篇有不良反应报道,但具体组别未知,仅有1篇报道试验组出现轻度腹泻2例和身体局部瘙痒1例。结论:黄芪注射液治疗脑梗死,在提高临床疗效、改善神经功能缺损评分方面可能优于对照组药物,但由于本系统评价纳入研究质量低且样本量小,药物安全性不明确,尚需高质量随机对照试验进一步验证。

相似文献/References:

[1]张永全,张惠玉,仝树坡,等.急性脑梗死肝阳暴亢证患者血脂及经颅多普勒检查结果的相关性研究[J].西部中医药,2011,24(11):38.
[2]朱晓娜,李天浩.调脂柔脉颗粒治疗动脉粥样硬化性脑梗死的疗效评价[J].西部中医药,2012,25(10):77.
 ZHU Xiao-na,LI Tian-hao.Evaluation on Clinical Efficacy of TiaoZhi RouMai Granules in Treating Atherosclerotic Cerebral Infarction[J].Western Journal of Traditional Chinese Medicine,2012,25(10):77.
[3]康庄.自拟中风活血化痰汤对急性脑梗死患者血清NSE、BDNF 水平的影响[J].西部中医药,2013,26(02):22.
 KANG Zhuang.Effects of Self-made ZhongFeng HuoXue HuaTanTang on Contents of Serum NSE and BDNF in Patients with Acute Cerebral Infarction[J].Western Journal of Traditional Chinese Medicine,2013,26(10):22.
[4]姚志瑞,焦富成,李霞.庆阳市脑梗死患者危险因素筛查及中医体质学分析[J].西部中医药,2013,26(09):53.
 YAO Zhirui,JIAO Fucheng,LI Xi.TCM Constitutions and Risk Factor Screening of Patients Suffering from Cerebral Infarction from Qingyang Municipality[J].Western Journal of Traditional Chinese Medicine,2013,26(10):53.
[5]任芳,徐厚谦△.黄芪注射液治疗糖尿病肾病随机对照试验报告质量评价[J].西部中医药,2013,26(12):1.
 REN Fang,XU Houqian.Quality Evaluation of the Report for Randomized Controlled Trials of HuangQi Injection in Treating Diabetic Nephropathy[J].Western Journal of Traditional Chinese Medicine,2013,26(10):1.
[6]王晓怀,潘文,康开彪,等.黄芪注射液治疗不稳定型心绞痛的系统评价[J].西部中医药,2013,26(10):61.
 WANG Xiaohuai,PAN Wen,KANG Kaibiao,et al.Systematic Review on HuangQi Injection in Treating Unstable Angina Pectoris[J].Western Journal of Traditional Chinese Medicine,2013,26(10):61.
[7]刘晓花.中医康复护理与常规内科护理对脑梗死患者功能康复的效果观察[J].西部中医药,2013,26(10):117.
 LIU Xiaohua.Observation on Therapeutic Effects of TCM Rehabilitation Care and Routine Care on Functional Rehabilitation of the Patients with Cerebral Infarction[J].Western Journal of Traditional Chinese Medicine,2013,26(10):117.
[8]任芳,徐厚谦△.黄芪注射液治疗糖尿病肾病有效性及安全性的系统评价[J].西部中医药,2014,27(01):77.
 REN Fang,XU Houqian.Systematic Review of the Effectiveness and Safety of HuangQi Injection in Treating Diabetic Nephropathy[J].Western Journal of Traditional Chinese Medicine,2014,27(10):77.
[9]焦富成.阿加曲班联合参芎葡萄糖治疗进展性脑梗死35例[J].西部中医药,2014,27(02):112.
 JIAO Fucheng.Argatroban and ShenXiong Glucose for 35 Cases of Progressive Cerebral Infarction[J].Western Journal of Traditional Chinese Medicine,2014,27(10):112.
[10]梁建,刘国华,李水桥,等.红花黄色素联合依达拉奉治疗急性脑梗死临床观察[J].西部中医药,2014,27(03):105.
 LIANG Jian,LIU Guohua,LI Shuiqiao,et al.Clinical Observation on Carthamin Yellow Combined with Edaravone in Treating Acute Cerebral Infarction[J].Western Journal of Traditional Chinese Medicine,2014,27(10):105.
[11]张征,刘长明,薛冰.丹参注射液与黄芪注射液对脑梗死大鼠急性期神经功能和梗死面积的影响[J].西部中医药,2017,30(01):17.
 ZHANG Zheng,LIU Changming,XUE Bing.The Influences of DanShen Injection and HuangQi Injection on Neurological Function and Infarct Size of Rats with Cerebral Infarction at Acute Stage[J].Western Journal of Traditional Chinese Medicine,2017,30(10):17.

备注/Memo

备注/Memo:
作者简介:王晓怀(1981—),男,硕士学位,医师。研究方向:循证医学、人群卫生干预及医学编辑。
更新日期/Last Update: 2014-10-15