[1]庞瑞康,范郁山.壮医药线点灸结合针刺治疗急性期带状疱疹疗效评价及对其镇痛机制的探讨[J].西部中医药,2022,35(08):62-65.[doi:10.12174/j.issn.2096-9600.2022.08.15]
 PANG Ruikang,FAN Yushan.Clinical Evaluation of Zhuang Medicine Medicated Thread Dotted Moxibustion and Acupuncture in the Treatment of Acute Herpes Zoster and Discussion on Analgesia Mechanism[J].Western Journal of Traditional Chinese Medicine,2022,35(08):62-65.[doi:10.12174/j.issn.2096-9600.2022.08.15]
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壮医药线点灸结合针刺治疗急性期带状疱疹疗效评价及对其镇痛机制的探讨
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
35
期数:
2022年08期
页码:
62-65
栏目:
民族医药
出版日期:
2022-08-15

文章信息/Info

Title:
Clinical Evaluation of Zhuang Medicine Medicated Thread Dotted Moxibustion and Acupuncture in the Treatment of Acute Herpes Zoster and Discussion on Analgesia Mechanism
作者:
庞瑞康1 范郁山12
1.广西中医药大学针灸推拿学院,广西 南宁 530001
2.广西中医药大学第一附属医院仁爱分院
Author(s):
PANG Ruikang1 FAN Yushan12
1.College of Acupuncture & Massage, Guangxi University of Chinese Medicine, Nanning 530001, China
2.Ren'ai Branch, The First Affiliated Hospital of Guangxi University of Chinese Medicine
关键词:
带状疱疹药线点灸针刺围刺镇痛机制壮医急性期
Keywords:
herpes zostermedicated thread dotted moxibustionacupuncturesurround needlinganalgesia mechanismmedicineacute
分类号:
R752.1+2
DOI:
10.12174/j.issn.2096-9600.2022.08.15
摘要:
目的评估壮医药线点灸结合针刺在急性期带状疱疹治疗方面的效果,并探讨其镇痛机制。 方法选取急性期带状疱疹患者72例,依照就诊次序随机分为观察组和对照组,每组36例。观察组给予壮医药线点灸结合针刺疗法,对照组给予常规针刺疗法,共治疗10天。比较两组证候改善情况(止疱时间、结痂时间、脱痂时间)、视觉模拟量表(visual analogue score,VAS)评分和血清白细胞介素6(interleukin-6,IL-6)、白细胞介素8(interleukin-8,IL-8)、P物质(substance P,SP)的含量,以及临床疗效、不良反应和神经后遗痛(postherpetic neuralgia,PHN)发生率。 结果观察组止疱时间、结痂时间、脱痂时间明显短于照组(P<0.05)。治疗后,两组VAS评分,血清IL-6、IL-8及SP含量均降低(P<0.05),且观察组下降程度大于对照组(P<0.05)。观察组总有效率[94.29%(33/35)]高于对照组[74.28%(26/35)](P<0.05)。两组均无明显不良反应发生,观察组治疗后第1、2、3个月PHN发生率均明显低于对照组(P<0.05)。 结论壮医药线点灸治疗带状疱疹可明显改善患者临床症状,降低PHN发生率,其镇痛机制可能与降低血清因子IL-6、IL-8及SP含量有关。
Abstract:
ObjectiveTo assess therapeutic effects of Zhuang medicine medicated thread dotted moxibustion and acupuncture in the treatment of acute herpes zoster, and discuss the analgesia mechanism. MethodsAll 72 patients were chosen, and randomized into the observation group and the control group according to the visiting order, 36 cases in each group. The observation group was given Zhuang medicine medicated thread dotted moxibustion and acupuncture, and the control group accepted conventional acupuncture, for ten days. To compare the improvements of the syndromes (the time of ceasing blister, the time of scabbing and the time of decrustation), VAS scores, the contents of IL-6, IL-8 and SP, clinical effects, the incidence of adverse reaction and PHN between both groups. ResultsThe observation group was apparently shorter than the control group in the time of ceasing blister, the time of scabbing and the time of decrustation (P<0.05). After the treatment, VAS scores, the contents of IL-6, IL-8 and SP were decreased in both groups (P<0.05), and the decrease of the observation group was greater than that of the control group (P<0.05). Total effective rate of the observation group was [94.29%(33/35)], higher than [74.28% (26/35)]of the control group (P<0.05). No obvious adverse reaction happened in both groups, the incidences of PHN at the first, second and third month of the observation group were lower than these of the control group after treatment notably (P<0.05). ConclusionZhuang medicine medicated thread dotted moxibus-tion in the treatment of herpes zoster could notably improve clinical symptoms, decrease the incidence of PHN, and its mechanism might be related to lowering the contents of IL-6, IL-8 and SP.

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备注/Memo

备注/Memo:
庞瑞康(1995—),男,硕士学位。研究方向:针灸方法与穴位主治规律。广西自然科学基金面上项目(2018JJA140336)。
更新日期/Last Update: 2022-08-15