[1]蒋永平.川丹消斑汤联合西药治疗代谢综合征颈动脉粥样硬化疗效观察[J].西部中医药,2013,26(05):100-102.
　JIANG Yongping.Clinical Observation on ChuanDan XiaoBanTang and Western Medicine in Treating Carotid Atherosclerosis Complicated with Metabolic Syndrome[J].Western Journal of Traditional Chinese Medicine,2013,26(05):100-102.
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川丹消斑汤联合西药治疗代谢综合征颈动脉粥样硬化疗效观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年05期
页码:
100-102
栏目:
出版日期:
2013-05-15

文章信息/Info

Title:
Clinical Observation on ChuanDan XiaoBanTang and Western Medicine in Treating Carotid Atherosclerosis Complicated with Metabolic Syndrome
文章编号:
1004-6852(2013)05-0100-03
作者:
蒋永平
甘谷县人民医院，甘肃 甘谷 741200
Author(s):
JIANG Yongping
Gangu County People's Hospital, Gangu 741200, China
关键词:
代谢综合征; 颈动脉粥样硬化; 川丹消斑汤; 辛伐他汀
Keywords:
metabolic syndrome (MS);  carotid atherosclerosis (CAS);  ChuanDan XiaoBanTang;  simvastatin
分类号:
R541.4
文献标志码:
B
摘要:
目的：观察自拟川丹消斑汤联合西药治疗代谢综合征(metabolic syndrome，MS)颈动脉粥样硬化(carotid atherosclerosis，CAS)的临床疗效。方法：将 200 例 MS 合并 CAS 的患者随机分为观察组和对照组各 100 例，治疗 6 个月后，观察临床疗效、血液流变学、颈动脉内 - 中膜厚度、颈动脉斑块厚度积分、心脑血管重要事件的发生及再住院率。结果：血液流变学、颈动脉内 - 中膜厚度、颈动脉斑块厚度积分观察组治疗前 后各指标改善明显(P＜0.05)；而对照组除血脂外，其他指标治疗前后差异无统计学意义(P＞0.05)；治疗后观察组总有效率为 91%，明显高于对照组的 60%，差异具有统计学意义(P＜0.01)。结论：川丹消斑汤联用西药治疗代谢综合征所致颈动脉粥样硬化疗效好，且无明显不良反应。
Abstract:
Objective: To observe clinical effects of self-made ChuanDan XiaoBanTang and western medicine in treating carotid atherosclerosis (CAS) complicated with metabolic syndrome (MS). Method: Two hundred patients were randomized into the observation group and the control group equally, after treating for six months, clinical effects, hemorheology, carotid intima-media thickness, carotid plaque thickness integral, the incidences of cardiovascular and cerebrovascular events as well as re-hospitalization rates were explored. Result: The changes of the indexes including hemorheology, carotid intima-media thickness and carotid plaque thickness integral of the observation group were markedly different before and after treating (P＜ 0.05); the differences between before and after treating in the indexes of the control group had no statistical meaning except blood fat (P＞ 0.05); after treating, total effective rate of the observation group was 91%, remarkably higher than 60% of the control group, the difference had statistical meaning (P＜ 0.01). Conclusion: ChuanDan XiaoBanTang and western medicine are the therapy effective in treating MS complicated with CAS without obvious adverse reaction.

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备注/Memo

备注/Memo:
收稿日期：2012-10-27 作者简介：蒋永平(1962—)，男，副主任医师。研究方向：心脑血管疾病的中西医结合诊治。
更新日期/Last Update: 2013-05-15