[1]贾潇,尤从新,颜春鲁,等.祛寒逐风合剂对阳虚型膝骨性关节炎患者内源性透明质酸水平的影响[J].西部中医药,2016,29(05):79-80.
　JIA Xiao,YOU Congxin,YAN Chunlu,et al.The Influence of QuHan ZhuFeng Mixture on the Levels of Endogenous Hyaluronic Acid of the Patients with Knee Osteoarthritis of Yang Deficiency Pattern[J].Western Journal of Traditional Chinese Medicine,2016,29(05):79-80.
点击复制

祛寒逐风合剂对阳虚型膝骨性关节炎患者内源性透明质酸水平的影响()
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
29
期数:
2016年05期
页码:
79-80
栏目:
出版日期:
2016-05-15

文章信息/Info

Title:
The Influence of QuHan ZhuFeng Mixture on the Levels of Endogenous Hyaluronic Acid of the Patients with Knee Osteoarthritis of Yang Deficiency Pattern
文章编号:
1004-6852(2016)05-0079-02
作者:
贾潇1，2，尤从新1，颜春鲁3，柴喜平1，柳海平1
1 甘肃省中医院，甘肃 兰州 730050； 2 天津中医药大学； 3 甘肃中医药大学
Author(s):
JIA Xiao1,2, YOU Congxin1, YAN Chunlu3, CHAI Xiping1, LIU Haiping1
1 Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China;2 Tianjin University of Traditional Chinese Medicine； 3 Gansu University of Traditional Chinese Medicine
关键词:
关节炎; 骨性; 膝; 阳虚型; 透明质酸钠; 祛寒逐风合剂
Keywords:
osteoarthritis;  bone;  knee;  Yang deficiency pattern;  sodium hyaluronate;  QuHan ZhuFeng mixture
分类号:
R681.8
文献标志码:
B
摘要:
目的：观察祛寒逐风合剂对阳虚型膝骨性关节炎(KOA)患者关节液及血清中透明质酸(HA)含量的影响。方法:将90例患者随机均分为A、B、C3组。A组采用祛寒逐风合剂治疗，B组采用透明质酸钠治疗；C组以祛寒逐风合剂联合透明质酸钠治疗。3组均连续治疗5周，观察治疗前后患者膝关节液和血清中HA的含量。结果：关节液HA水平3组治疗前后组内比较，差异有统计学意义(P＜0.05)，治疗后组间比较差异有统计学意义(P＜0.05)。血清中HA含量A、C组治疗前后组内比较，差异有统计学意义(P＜0.05)，治疗后组间比较差异有统计学意义(P＜0.05)。结论：口服祛寒逐风合剂联合关节腔内注射透明质酸钠治疗阳虚型KOA能升高患者膝关节滑液中HA含量，降低血清中HA含量。
Abstract:
Objective: To observe the effects of QuHan ZhuFeng mixture on the contents of hyaluronic acid (HA) in joint fluid and the serum of the patients with knee osteoarthritis (KOA) of Yang deficiency pattern. Methods: Ninety patients were randomized into the groups of A, B and C. Group A adopted QuHan ZhuFeng mixture, group B sodium hyaluronate, and group C QuHan ZhuFeng mixture combined with sodium hyaluronate. Three groups were treated for five weeks consecutively. The contents of HA in joint fluid and the serum were observed before and after treating. Results: The difference showed statistical meaning in the comparisons of the levels of HA in joint fluid between before and after treating in three groups (P＜0.05), the difference had statistical meaning in the comparisons among three groups after treating (P＜0.05). The difference had statistical meaning in the comparisons of HA contents in the serum between before and after treating in the groups A and C (P＜0.05), the difference presented statistical meaning in the comparison between A and C after treating (P＜0.05). Conclusion: Oral administration of QuHan ZhuFeng mixture combined with injecting HA into joint cavity could raise HA contents in knee joint synovia and decrease HA contents in the serum in the treatment of the patients with KOA of Yang deficiency pattern.

相似文献/References:

[1]覃仕化,汪悦.痹痛灵颗粒对胶原诱导性关节炎大鼠血清及滑膜组织匀浆中IL-2的影响[J].西部中医药,2011,24(11):9.
[2]赵军,邢涛,董林,等.骨刺消巴布剂对兔膝骨性关节炎IL-1β和TNF-α的影响*[J].西部中医药,2012,25(11):25.
　ZHAO Jun,XING Tao,DONG Lin,et al.Effects of GuCiXiao Cataplasm on IL-1β and TNF-α of Rabbits with Knee Osteoarthritis[J].Western Journal of Traditional Chinese Medicine,2012,25(05):25.
[3]雷斌,宋敏△,刘宗权.阶梯疗法在膝骨性关节炎治疗中的指导意义[J].西部中医药,2012,25(11):116.
　LEI Bin,SONG Min,LIU Zong-quan.Guiding Significance of Rescue by Stages in the Treatment of Knee Osteoarthritis[J].Western Journal of Traditional Chinese Medicine,2012,25(05):116.
[4]唐瑛,肖力强,江花,等.中药复方敷擦外治类风湿性关节炎的用药规律研究*[J].西部中医药,2013,26(05):57.
　TANG Ying,XIAO Liqiang,JIANG Hua,et al.Research on the Law of Medicine Application of TCM Compound in Treating Rheumatoid Arthritis for External Use[J].Western Journal of Traditional Chinese Medicine,2013,26(05):57.
[5]姚兴璋,李兴勇△.从流行病学浅析膝关节骨性关节炎的危险因素[J].西部中医药,2012,25(09):132.
　YAO Xing-zhang,LI Xing-yong.Analysis of Epidemiology on Risk Factors of Knee Osteoarthritis[J].Western Journal of Traditional Chinese Medicine,2012,25(05):132.
[6]张振顺.宣痹汤合二妙散加减治疗类风湿性关节炎的临床观察[J].西部中医药,2012,25(08):77.
　ZHANG Zhen-shun.Clinical Observation on Modified XuanBiTang and ErMiaoSan in Treating Rheumatoid Arthritis[J].Western Journal of Traditional Chinese Medicine,2012,25(05):77.
[7]张勇.四妙永安汤加味治疗急性痛风性关节炎140例[J].西部中医药,2012,25(07):59.
　ZHANG Yong.Clinical Observation on Modified SiMiao YongAnTang in Treating 140 Cases of Acute Gouty Arthritis[J].Western Journal of Traditional Chinese Medicine,2012,25(05):59.
[8]胡学玲.中药塌渍配合红外线治疗类风湿性关节炎临床观察[J].西部中医药,2012,25(07):96.
　HU Xue-ling.Clinical Observation on Hot Compress with Herbs and Infrared in Treating Rheumatoid Arthritis[J].Western Journal of Traditional Chinese Medicine,2012,25(05):96.
[9]侯建平,王亚军,严亚峰,等.虎杖提取物抗动物高尿酸血症的实验研究[J].西部中医药,2012,25(05):21.
　HOU Jian-ping,WANG Ya-jun,YAN Ya-feng,et al.Study of Polygonum Cuspidatum Extract on Anti-Hyperuricemia in Rats and Mice[J].Western Journal of Traditional Chinese Medicine,2012,25(05):21.
[10]董三明.针刺配合中药熏洗治疗退行性膝关节炎30例[J].西部中医药,2013,26(09):106.
　DONG Sanming.Needling and TCM Fumigation in Treating 30 Cases of Degenerative Osteoarthritis[J].Western Journal of Traditional Chinese Medicine,2013,26(05):106.
[11]陈志龙,徐霞,申建军,等.中药洗剂外敷配合舒血宁注射液治疗膝关节骨性关节炎80例[J].西部中医药,2011,24(11):31.
[12]尤从新.樊成虎教授治疗膝关节骨性关节炎经验[J].西部中医药,2014,27(12):33.
[13]周明旺,王晓萍,李盛华,等.膝骨性关节炎中医体质类型与IGF-1表达的相关性研究[J].西部中医药,2015,28(12):1.
[14]李盛华,杨文博,周明旺,等.调衡理念与陇中正骨手法关系探讨———以早期膝骨性关节炎为例[J].西部中医药,2017,30(08):22.
　LI Shenghua,YANG Wenbo,ZHOU Mingwang,et al.A Discussion on the Relationship between Regulating Concept and Longzhong Bone-setting Manipulation by Taking Early Knee Osteoarthritis as an Example[J].Western Journal of Traditional Chinese Medicine,2017,30(05):22.
[15]胡小永.金乌骨通胶囊治疗膝关节骨性关节炎40例[J].西部中医药,2017,30(08):98.
　HU Xiaoyong.Treating 40 Cases of Knee Osteoarthritis by JinWu GuTong Capsules[J].Western Journal of Traditional Chinese Medicine,2017,30(05):98.
[16]余新华,郑汉印,徐丽.透明质酸钠联合六味地黄丸治疗老年膝骨性关节炎50例[J].西部中医药,2017,30(08):120.
　YU Xinhua,ZHENG Hanyin,XU Li.Sodium Hyaluronate Combined with LiuWei DiHuang Pills in Treating 50 Senile Patients with Knee Osteoarthritis[J].Western Journal of Traditional Chinese Medicine,2017,30(05):120.
[17]石耀武,李延红,张宏蕾,等.活络止痛软膏联合针灸治疗肝肾不足型膝骨关节炎80例[J].西部中医药,2017,30(08):137.
　SHI Yaowu,LI Yanhong,ZHANG Honglei,et al.HuoLuo ZhiTong Ointment Combined with Acupuncture in Treating 80 Cases of Knee Osteoarthritis of Liver-kidney Deficiency Pattern[J].Western Journal of Traditional Chinese Medicine,2017,30(05):137.
[18]张文进,孙志华,李永吉,等.丹参注射液对膝骨性关节炎关节液及炎症血清细胞因子水平的影响[J].西部中医药,2019,32(02):21.
　ZHANG Wenjin,SUN Zhihua,LI Yongji,et al.Influence of DanShen Injection on the Level of Serum Cytokines and Joint Fluid of Knee Osteoarthritis[J].Western Journal of Traditional Chinese Medicine,2019,32(05):21.
[19]李海洋,刘智斌,李彬锋,等.基于症状、体征评分量表评价“膝五刀”治疗膝骨性关节炎的临床疗效[J].西部中医药,2020,33(06):108.[doi:10.12174/j.issn.1004-6852.2020.06.29]
　LI Haiyang,LIU Zhibin,LI Binfeng,et al.Clinical Effects of "Knee Five Knives" in the Treatment of Knee Osteoarthritis Evaluated by the Scales of Symptoms and Body Signs[J].Western Journal of Traditional Chinese Medicine,2020,33(05):108.[doi:10.12174/j.issn.1004-6852.2020.06.29]
[20]潘婷,王颖,范东英,等.火龙疗法干预早期膝痹病患者效果评价[J].西部中医药,2022,35(06):118.[doi:10.12174/j.issn.2096-9600.2022.06.29]
　PAN Ting,WANG Ying,FAN Dongying,et al.Evaluation of the Effects of Fire Dragon Therapy in the Intervention of Pain in Patients with Early Knee Arthralgia[J].Western Journal of Traditional Chinese Medicine,2022,35(05):118.[doi:10.12174/j.issn.2096-9600.2022.06.29]

备注/Memo

备注/Memo:
收稿日期：2015-02-27作者简介：贾潇(1983—)，男，硕士学位，主治医师。研究方向：骨与关节损伤的诊治。
更新日期/Last Update: 2016-05-15