[1]宋薇.复方红景天口含片质量标准研究[J].西部中医药,2018,31(07):34-38.
　SONG Wei.Research on Quality Standard of Compound HongJingTian Buccal Tablets[J].Western Journal of Traditional Chinese Medicine,2018,31(07):34-38.
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复方红景天口含片质量标准研究()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年07期
页码:
34-38
栏目:
出版日期:
2018-07-15

文章信息/Info

Title:
Research on Quality Standard of Compound HongJingTian Buccal Tablets
文章编号:
1004-6852(2018)07-0034-05
作者:
宋薇
甘肃省中医院，甘肃 兰州 730050
Author(s):
SONG Wei
Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China
关键词:
复方红景天口含片; 质量标准; 红景天苷; 酪醇; 二苯乙烯苷; TLC; HPLC
Keywords:
compound HongJingTian buccal tablets;  quality standard;  rhodioside;  butyl alcohol;  Stilbene glycoside;  TLC;  HPLC
分类号:
R282
文献标志码:
A
摘要:
目的：建立复方红景天口含片的质量标准。方法：采用薄层色谱(TLC)法对处方中红景天、何首乌进行定性鉴别；采用高效液相色谱法测定红景天中红景天苷和酪醇以及何首乌中二苯乙烯苷的含量。结果：TLC斑点清晰，阴性对照无干扰。红景天苷在0.642～5.136 μg范围内呈良好的线性关系，r=0.9997，平均加样回收率为100.29%，RSD=1.69%(n=9)；酪醇在3.6～36.0 μg范围内与吸收峰峰面积积分值呈良好的线性关系，r=0.999 1；平均加样回收率为99.46%，RSD=2.25%(n=9)；二苯乙烯苷在0.162～1.944 μg范围内与吸收峰峰面积积分值呈良好的线性关系，r=0.999 3；平均加样回收率为100.34%，RSD为1.75%(n=9)。结论：所建标准可用于复方红景天口含片的质量控制。
Abstract:
Objective: To establish the quality standard of compound HongJingTian buccal tablets. Methods: Thin-layer chromatography (TLC) was used to identify HongJingTian (Rhodiola rosea L.) and HeShouWu ［Fallopia multiflora(Thunb.) Harald] in the prescription qualitatively; high performance liquid chromatography(HPLC) was adopted to detect the contents of Stilbene glycoside in HeShouWu, rhodioside and butyl alcohol in HongJingTian. Results: TLC spots were clear, and the blank test showed no interference. Rhodioside presented good linear relationship in the range between 0.642 and 5.136 μg, r=0.999 7, average sample recovery was 100.29%, RSD=1.69% (n=9); butyl alcohol showed good linear relationship in the range between 3.6 and 36.0μg and integral quantity of absorption peak area, r=0.999 1, average sample recovery was 99.46%, RSD=2.25%(n=9); Stilbene glycoside presented good linear relationship in the range between 0.162 and 1.944 μg and integral quantity of absorption peak area, r=0.999 3, average sample recovery was 100.34%, RSD=1.75% (n=9). Conclusion: The established standard could be used for quality control of compound HongJingTian buccal tablets.

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备注/Memo

备注/Memo:
收稿日期：2017-10-25 *基金项目：兰州市生物医药与中药现代化项目(编号2008-1-177)。 作者简介：宋薇(1986—)，女，硕士学位，主管中药师。研究方向：中药化学及中药质量标准的建立。
更新日期/Last Update: 2018-07-15