[1]张明倩,崔爽,梁五林,等.急性心肌梗死合并抑郁症的研究进展[J].西部中医药,2023,36(02):124-128.[doi:10.12174/j.issn.2096-9600.2023.02.29]
　ZHANG Mingqian,CUI Shuang,LIANG Wulin,et al.Research Progress of Acute Myocardial Infarction Complicated with Depression[J].Western Journal of Traditional Chinese Medicine,2023,36(02):124-128.[doi:10.12174/j.issn.2096-9600.2023.02.29]
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急性心肌梗死合并抑郁症的研究进展
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
36
期数:
2023年02期
页码:
124-128
栏目:
出版日期:
2023-02-15

文章信息/Info

Title:
Research Progress of Acute Myocardial Infarction Complicated with Depression
作者:
张明倩, 崔爽, 梁五林, 张硕峰
北京中医药大学中药学院，北京 102488
Author(s):
ZHANG Mingqian, CUI Shuang, LIANG Wulin, ZHANG Shuofeng
Pharmacy College, Beijing University of Chinese Medicine, Beijing 102488, China
关键词:
心肌梗死; 急性; 抑郁症; 双心医学; 研究进展
Keywords:
myocardial infarction;  acute; depression; psycho-cardiology; research progress
分类号:
R542.2+3
DOI:
10.12174/j.issn.2096-9600.2023.02.29
文献标志码:
A
摘要:
从心肌梗死与抑郁症的关系入手，探讨心肌梗死合并抑郁症的病理生理机制，并对治疗方法进行论述。认为心肌梗死与抑郁症之间的双向关系已经明确，两者相互影响，恶性循环，虽其发病机制尚未明确，但大概包括炎症反应学说、细胞凋亡学说、血小板活化和5-HT作用下丘脑-垂体-肾上腺素轴功能亢进、内皮功能障碍等几种假说。治疗方式主要是在冠心病二级治疗基础上结合抗抑郁药物并辅以非药物疗法。此外，“双心医学”护理模式可通过心理疗法、运动疗法、生物反馈疗法等非药物疗法和药物疗法发挥作用。
Abstract:
The paper explores pathophysiological mechanism of myocardial infarction complicated with depression, and therapeutic methods from the connections between myocardial infarction and depression. It is believed that bidirectional relationship between myocardial infarction and depression has been confirmed, they interacting with each other and forming a vicious circle, though its pathogenesis is not clear yet, roughly containing the theory of inflammatory response, cellular apoptosis, platelet activation, 5-HT-induced hyperfun-ction of hypothalamic-pituitary-adrenalin axis, endothelial dysfunction and other hypotheses. Therapeutic methods mainly adopt secondary treatment of coronary heart disease and anti-depressant drugs, supplemented by non-pharmaceutical therapy. In addition, nursing mode of psycho-cardiology could work through non-pharmaceutical therapy such as psychological therapy, motortherapy, biofeedback therapy, and drug therapy.

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备注/Memo

备注/Memo:
张明倩（1996—），女，在读硕士研究生。研究方向：中药药理学。西藏自治区重大科技专项（XZ201801-GA-16）。
更新日期/Last Update: 2023-02-15