[1]马莉,黄咏梅,王萍.解毒凉血汤联合刺络放血对寻常型银屑病疗效及患者血清CRP和PCT水平的影响[J].西部中医药,2023,36(11):127-130.[doi:10.12174/j.issn.2096-9600.2023.11.29]
　MA Li,HUANG Yongmei,WANG Ping.Curative Effects of Jiedu Liangxue Tang Combined with Bloodletting in the Treatment of Psoriasis Vulgaris and Its Influence on the Levels of Serum CRP and PCT[J].Western Journal of Traditional Chinese Medicine,2023,36(11):127-130.[doi:10.12174/j.issn.2096-9600.2023.11.29]
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解毒凉血汤联合刺络放血对寻常型银屑病疗效及患者血清CRP和PCT水平的影响
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
36
期数:
2023年11期
页码:
127-130
栏目:
出版日期:
2023-11-15

文章信息/Info

Title:
Curative Effects of Jiedu Liangxue Tang Combined with Bloodletting in the Treatment of Psoriasis Vulgaris and Its Influence on the Levels of Serum CRP and PCT
作者:
马莉, 黄咏梅, 王萍
西宁市第一人民医院皮肤科，青海 西宁 810000
Author(s):
MA Li, HUANG Yongmei, WANG Ping
Department of Dermatology, The First People's Hospital of Xining, Xining 810000, China
关键词:
寻常型银屑病; C反应蛋白; 降钙素原; 解毒凉血汤; 刺络放血
Keywords:
psoriasis vulgaris; CRP; calcitonin; bloodletting
分类号:
R246.7
DOI:
10.12174/j.issn.2096-9600.2023.11.29
文献标志码:
B
摘要:
目的研究解毒凉血汤联合刺络放血对寻常型银屑病疗效及患者血清C反应蛋白（C-reaction protein，CRP））和降钙素原（procalcitonin，PCT）水平的影响。 方法将150例寻常型银屑病患者随机分为两组各75例。对照组服用阿维A胶囊，观察组联用解毒凉血汤和刺络放血疗法。比较两组患者T淋巴细胞亚群水平、血清CRP、PCT水平、生活质量、中医症状积分和有效率。 结果观察组有效率为96.00%（72/75），高于对照组的74.67%（56/75）（P＜0.05）；治疗后两组患者外周血CD3+、CD4+/CD8+和CD4+水平均升高，CD8+水平、血清CRP和PCT水平及DLQI评分和中医症状积分均降低（P＜0.05），观察组上述指标变化均优于对照组（P＜0.05）。 结论解毒凉血汤联合刺络放血能抑制寻常型银屑病患者血清CRP和PCT表达，改善T淋巴细胞分布，减轻患者中医症状，改善生活质量。
Abstract:
ObjectiveTo study clinical effects of Jiedu Liangxue Tang and bloodletting in treating psoriasis vulgaris and its impacts on the levels of CRP and PCT. MethodsAll 150 patients were randomized into two groups. The control group took acitretin capsules, and the observation group adopted Jiedu Liangxue Tang and bloodletting. To compare the levels of T lymphocyte subsets, serum CPR and PCT, quality of life, TCM symptoms integrals and effective rate between both groups. ResultsThe effective rate of the observation group was 96.00%（72/75）, higher than 74.67%（56/75） of the control group (P<0.05); after the treatment, the levels of CD3+, CD4+/ CD8+ and CD4+ increased in peripheral blood in both groups while the levels of CD8+, serum CRP and PCT, DLQI scores and TCM symptom integrals decreased (P<0.05); the changes of the indexes of the observation group were better than these of the control group (P<0.05). ConclusionJiedu Liangxue Tang and bloodletting in treating psoriasis vulgaris could inhibit the expressions of CRP and PCT, improve the distribution of T lymphocytes, alleviate the patients' symptoms and improve quality of life.

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备注/Memo

备注/Memo:
马莉（1978—），女，副主任医师。研究方向：皮肤科常见病及损容性皮肤病的中西医结合治疗。山东省自然科学基金（ZR2014HL063）。 西宁市科技计划项目（2015-K-25）。
更新日期/Last Update: 2023-11-15