[1]史振华,王晓萍,张朋威,等.基于痰瘀互结探讨股骨头坏死的病因病机及临床应用[J].西部中医药,2026,39(02):26-29.[doi:10.12174/j.issn.2096-9600.2026.02.07]
　SHI Zhenhua,WANG Xiaoping,ZHANG Pengwei,et al.The Etiology and the Pathogenesis of ONFH and Its Clinical Application Based on Phlegm-Stasis Binding[J].Western Journal of Traditional Chinese Medicine,2026,39(02):26-29.[doi:10.12174/j.issn.2096-9600.2026.02.07]
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基于痰瘀互结探讨股骨头坏死的病因病机及临床应用()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
39
期数:
2026年02期
页码:
26-29
栏目:
学术探讨
出版日期:
2026-02-15

文章信息/Info

Title:
The Etiology and the Pathogenesis of ONFH and Its Clinical Application Based on Phlegm-Stasis Binding
作者:
史振华1, 王晓萍2, 张朋威1, 高海源1, 杨星1
1.甘肃中医药大学，甘肃 兰州 730000
2.甘肃省中医院，甘肃 兰州 730050
Author(s):
SHI Zhenhua1, WANG Xiaoping2, ZHANG Pengwei1, GAO Haiyuan1, YANG Xing1
1.Gansu University of Chinese Medicine, Lanzhou 730000, China
2.Gansu Provincial Hospital of Traditional Chinese Medicine, Lanzhou 730050, China
关键词:
股骨头坏死; 痰瘀互结; 病因病机; 病理变化; 化痰祛瘀法
Keywords:
osteonecrosis of the femoral head; phlegm-stasis binding; the etiology and pathogenesis; pathological changes; phlegm-resolving stasis-eliminating method
分类号:
R274.9
DOI:
10.12174/j.issn.2096-9600.2026.02.07
文献标志码:
A
摘要:
对痰、瘀等因素与股骨头坏死（osteonecrosis of the femoral head，ONFH）的相关病因病机以及化痰祛瘀法治疗ONFH的机制研究进行梳理，指出痰瘀互结是ONFH常见致病因素，亦是ONFH重要的病因病机，痰瘀互结能够诱发股骨头脂代谢紊乱，阻碍股骨头血液供应，影响骨髓微环境变化，引发骨细胞代谢失衡，且贯穿于ONFH发生发展的全过程。中医药在辨证施治的基础上结合“化痰祛瘀”法治疗ONFH可能疗效更佳；同时应注重整体观念，考虑痰瘀形成的病机，从肝、脾、肾等多脏腑进行综合论治。
Abstract:
By reviewing the correlation between the etiology and pathogenesis of ONFH with factors such as phlegm and stasis, the study on the mechanism of phlegm-resolving stasis-eliminating method in the treatment of ONFH, it was pointed out that phlegm-stasis binding served as the common pathogenic factor for ONFH, and the important cause and pathogenesis of the disease. Phlegm-stasis binding could induce lipid metabolism disorders of the femoral head, impair blood supply to the femoral head, and trigger changes in the bone marrow microenvironment, resulting in bone cell metabolic imbalance, throughout the entire process of ONFH occurrence and development. On the foundation of syndrome differentiation and treatment, the combination of TCM and phlegm-resolving stasis-eliminating method is effective in treating ONFH; meanwhile, the concept of holism should be emphasized, and the pathogenesis of phlegm-stasis formation should be considered, so as to treat the disease from liver, spleen and kidney comprehensively.

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备注/Memo

备注/Memo:
国家自然科学基金（82360942，82060876）；甘肃省科技计划项目（18JR2FA009）。史振华（1998—），男，在读硕士研究生。研究方向：中医药防治骨与关节疾病。
更新日期/Last Update: 2026-02-15