[1]李树纲,柴守华,高新艳,等.黄芪煎剂联合丹红注射液治疗慢性肾炎临床观察[J].西部中医药,2013,26(07):71-73.
　LI Shugang,CHAI Shouhua,GAO Xinyan,et al.On Clinical Efficacy of HuangQi Decoction and DanHong Injection for Chronic Glomerulonephritis[J].Western Journal of Traditional Chinese Medicine,2013,26(07):71-73.
点击复制

黄芪煎剂联合丹红注射液治疗慢性肾炎临床观察
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年07期
页码:
71-73
栏目:
出版日期:
2013-07-15

文章信息/Info

Title:
On Clinical Efficacy of HuangQi Decoction and DanHong Injection for Chronic Glomerulonephritis
文章编号:
1004-6852(2013)07-0071-03
作者:
李树纲，柴守华，高新艳，贺万彬，马永鸿
敦煌市医院中医康复科，甘肃 敦煌 736200
Author(s):
LI Shugang, CHAI Shouhua, GAO Xinyan, HE Wanbin, MA Yonghong
TCM Rehabilitation Department of Dunhuang Municipality Hospital, Dunhuang 736200, China
关键词:
缬沙坦; 黄芪; 丹红注射液; 慢性肾小球肾炎
Keywords:
valsartan;  HuangQi (radix astragali);  DanHong injection;  chronic glomerulonephritis (CGN)
分类号:
R692.3
文献标志码:
A
摘要:
目的：探讨黄芪煎剂联合丹红注射液治疗慢性肾炎(CGN)的临床疗效。方法：随机将70例慢性肾炎患者分成治疗组(35例)和对照组(35例)。对照组给予缬沙坦80～240 mg/d，联合依那普利10～30 mg/d，同时给予潘生丁、激素、细胞毒药物等常规治疗。治疗组在此基础上配合黄芪煎剂口服及丹红注射液静脉滴注，连续用药30天，观测2组治疗前后的24小时尿蛋白定量、尿素氮(BUN)、肌酐(Scr)、血白细胞、红细胞及尿红细胞，并比较组间差异，同时评价临床疗效。结果：治疗组总有效率(94.29%)显著高于对照组(80.00%)，差异有统计学意义(P＜0.05)。2组治疗后24小时尿蛋白定量、BUN、Scr均较治疗前明显降低，治疗前后差异有统计学意义(P＜0.05);治疗组治疗后24小时尿蛋白定量、Scr与对照组比较差异有统计学意义(P＜0.05)；治疗组治疗前后的血WBC差异无统计学意义(P＞0.05)，血RBC、尿RBC治疗前后差异有统计学意义(P＜0.05)。结论：黄芪煎剂联合丹红注射液治疗CGN效果显著。
Abstract:
Objective: To discuss clinical efficacy of HuangQi decoction and DanHong injection in treating chronic glomerulonephritis (CGN). Method: Seventy patients were divided into the treatment group and the control group. The control group took valsartan, 80 to 240mg/d, enalapril, 10 to 30 mg/d, and rountine western medicine including dipyridamole, hormone and cytotoxic drugs. The patients in the treatment group were given with oral HuangQi decoction and intravenous dripping of DanHong injection, for 30 consecutive days, 24 hours quantitative test for urinary protein, blood urine nitrogen(BUN), creatintine(Scr), blood white blood cells, red blood cells and urine red blood cells were detected before and after treating in both groups, the differences between both groups were compared to assess clinical effects. Result: Total effective rate of the treatment group (94.29%) was higher than that of the control group (80.00%), the difference demonstrated significant meaning (P＜0.05). 24 hours quantitative test for urinary protein, BUN and Scr were decreased after treating than before treating in both groups, the difference between both groups showed statistical meaning(P＜0.05); the difference in blood WBC of the treatment group between before and after treating had no statistical meaning (P＞0.05), the difference in blood RBC and urine RBC between before and after treating had statistical meaning (P＜0.05). Conclusion: HuangQi decoction and DanHong injection in treating CGN could obtain notable effects.

相似文献/References:

[1]陈郁林,李建银,杜晶晶,等.甘肃陇西不同地区黄芪中重金属含量的测定[J].西部中医药,2012,25(11):12.
　CHEN Yu-lin,LI Jian-yin,DU Jing-jing,et al.Content Determination of Heavy Metals in HuangQi from Different Districts of LongXi[J].Western Journal of Traditional Chinese Medicine,2012,25(07):12.
[2]师金凤,李海龙,王红蕾,等.黄芪及其有效成分防治消化道肿瘤的文献评价*[J].西部中医药,2014,27(08):44.
[3]刘涛.缬沙坦联合复方丹参滴丸对早期2型糖尿病肾病患者尿微量白蛋白的影响[J].西部中医药,2015,28(05):106.
[4]郭菊梅,杨光,陈慧昱,等.红芪替换黄芪后益气养血汤对老龄鼠抗氧化损伤及抗免疫衰老作用的比较研究*[J].西部中医药,2014,27(08):7.
　GUO Jumei,YANG Guang,CHEN Huiyu,et al.Comparative Study between YiQi YangXue Tang and the One Replacing HuangQi by HongQi on Anti-oxidative Damage and Anti-aging of Senile Rats[J].Western Journal of Traditional Chinese Medicine,2014,27(07):7.
[5]张军武,赵琦,王昌利.不同生长年限黄芪中黄芪总黄酮含量考察[J].西部中医药,2012,25(12):18.
　ZHANG Jun-wu,ZHAO Qi,WANG Chang-li.Content Determination of Total Flavonoids from Radix Astragali of Different Growth Years[J].Western Journal of Traditional Chinese Medicine,2012,25(07):18.
[6]颜春鲁,陈丽△,胡继宏,等.黄芪及其提取物对矽肺模型大鼠支气管肺泡灌洗液MMP-2、MMP-9表达的影响[J].西部中医药,2015,28(10):22.
[7]尚虎山,刘效瑞,王富胜,等.药用植物黄芪品种道地产区产量的AMMI模型分析[J].西部中医药,2016,29(01):8.
　SHANG Hushan,LIU Xiaorui,WANG Fusheng,et al.AMMI Model of the Yield of Medicinal Plants HuangQi in Genuine Producing Areas[J].Western Journal of Traditional Chinese Medicine,2016,29(07):8.
[8]朱仁愿,邱国玉,张彩霞,等.评定ICP-MS法测定黄芪中重金属含量的不确定度[J].西部中医药,2017,30(03):32.
　ZHU Renyuan,QIU Guoyu,ZHANG Caixia,et al.The Uncertainty Evaluation of Determination of Heavy Metals in HuangQi by ICP-MS[J].Western Journal of Traditional Chinese Medicine,2017,30(07):32.
[9]赵坚毅,田立东△,潘曌曌.黄芪、小蓟对NF-κB信号通路的影响[J].西部中医药,2017,30(04):22.
　ZHAO Jianyi,TIAN Lidong,PAN Zhaozhao.The Influences of HuangQi and XiaoJi on NF-κB Signal Channel[J].Western Journal of Traditional Chinese Medicine,2017,30(07):22.
[10]杨长花,程芬,李慧,等.4个主要黄芪产地黄芪质量比较[J].西部中医药,2019,32(01):27.
　YANG Changhua,CHENG Fen,LI Hui,et al.Quality Comparisons of HuangQi Collected from Four Major Producing Areas[J].Western Journal of Traditional Chinese Medicine,2019,32(07):27.

备注/Memo

备注/Memo:
收稿日期：2012-12-04 作者简介：李树纲(1977—)，男，主治医师。研究方向：肾脏疾病的中西医结合诊治。
更新日期/Last Update: 2013-07-15