[1]何永成,马国杰.中医分期治疗溃疡性结肠炎43例[J].西部中医药,2018,31(08):81-83.
　HE Yongcheng,MA Guojie.TCM Phased Therapy in Treating 43 Cases of Ulcerative Colitis[J].Western Journal of Traditional Chinese Medicine,2018,31(08):81-83.
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中医分期治疗溃疡性结肠炎43例()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年08期
页码:
81-83
栏目:
出版日期:
2018-08-15

文章信息/Info

Title:
TCM Phased Therapy in Treating 43 Cases of Ulcerative Colitis
文章编号:
004-6852(2018)08-0081-03
作者:
何永成，马国杰
临夏回族自治州中医院内科，甘肃 临夏 731100
Author(s):
HE Yongcheng, MA Guojie
Department of Internal Medicine,Linxia Hui Autonomous Prefecture Hospital of Chinese Medicine, Linxia 731100, China
关键词:
结肠炎; 溃疡性; 辨证论治; 肿瘤坏死因子α; 白介素6; 白介素8
Keywords:
Objective: To observe clinical effects of TCM phased therapy in the treatment for ulcerative colitis (UC). Methods: All 83 UC patients were randomized into the observation group (43 cases) and the control group (40 cases);  the observation group used TCM p
分类号:
R516.1
文献标志码:
B
摘要:
目的：观察中医分期治疗溃疡性结肠炎(UC)的临床疗效。方法：将83例UC患者随机分为观察组43例、对照组40例，观察组采用中医分期辨证论治，对照组采用美沙拉嗪肠溶片治疗，观察2组治疗前后血清肿瘤坏死因子α(TNF-α)、白介素6(IL-6)、白介素8(IL-8)变化情况及药物安全性、临床疗效和复发率。结果：血清TNF-α、IL-6、IL-8水平治疗前后2组组内比较，差异有统计学意义(P＜0.05)；治疗后2组组间比较，差异无统计学意义(P＞0.05)。缓解率2组比较，差异无统计学意义(P＞0.05)；复发率2组比较，差异有统计学意义(P＜0.05)。安全性评价观察组优于对照组(P＜0.05)。结论：中医分期治疗UC患者，临床疗效与西医治疗相当，可有效改善血清中炎症因子水平，明显提高药物安全性，降低复发率。
Abstract:
Objective: To observe clinical effects of TCM phased therapy in the treatment for ulcerative colitis (UC). Methods: All 83 UC patients were randomized into the observation group (43 cases) and the control group (40 cases), the observation group used TCM phased therapy based on syndrome differentiation and treatment, the control group adopted mesalazine enteric-coated tablets, the recurrence rate, curative effects, drug safety, the changes of IL-8, IL-6 and TNF-α of both groups were observed before and after treating. Results: The difference had statistical meaning in the comparisons of the levels of IL-8, IL-6 and TNF-α within the groups between before and after treating (P＜0.05); the difference had no statistical meaning in the comparisons between both groups after treating (P＞0.05). The difference showed no statistical meaning in the comparison of the remission rate between both groups (P＞0.05); the difference presented statistical meaning in the comparisons of the recurrence rate between both groups (P＜0.05). The observation group was superior to the control group in assessing the safety (P＜0.05). Conclusion: TCM phased therapy in the treatment for UC could effectively improve the levels of inflammatory factors in the serum, obviously raise drug safety and decrease the recurrence rate, and its effects are equivalent to these of Western medicine.

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备注/Memo

备注/Memo:
收稿日期：2018-02-15 作者简介：何永成(1964—)，男，副主任医师。研究方向：内科疾病的中医诊治。
更新日期/Last Update: 2018-08-15