[1]郭守强.不同时间点肠内营养支持联合清胰汤对重度急性胰腺炎患者免疫因子的影响[J].西部中医药,2020,33(04):115-117.[doi:10.12174/j.issn.1004-6852.2020.04.35]
　GUO Shouqiang.Influence of Enteral Nutritional Support at Different Time Points Combined with Qingyi Tang on Immunologic Factors in the Patients with Severe Acute Pancreatitis[J].Western Journal of Traditional Chinese Medicine,2020,33(04):115-117.[doi:10.12174/j.issn.1004-6852.2020.04.35]
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不同时间点肠内营养支持联合清胰汤对重度急性胰腺炎患者免疫因子的影响
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
33
期数:
2020年04期
页码:
115-117
栏目:
出版日期:
2020-04-15

文章信息/Info

Title:
Influence of Enteral Nutritional Support at Different Time Points Combined with Qingyi Tang on Immunologic Factors in the Patients with Severe Acute Pancreatitis
文章编号:
1004-6852(2020)04-0115-03
作者:
郭守强
秦安县人民医院急诊科,甘肃 秦安 741600
Author(s):
GUO Shouqiang
Emergency Department, Qin′an County People′s Hospital, Qin′an 741600, China
关键词:
肠内营养; 清胰汤; 胰腺炎; 淀粉酶
Keywords:
enteral nutrition;  Qingyi Tang;  pancreatitis;  diastase
分类号:
R657.5+1
DOI:
10.12174/j.issn.1004-6852.2020.04.35
文献标志码:
B
摘要:
目的:比较不同时间点肠内营养支持联合清胰汤对重度急性胰腺炎患者免疫因子的影响及临床治疗效果。方法:将92例患者按照就诊顺序随机分为对照组，观察组A、B、C，每组23例。观察组A、B、C均给予常规治疗，且观察组A于入院第1天给予肠内营养支持，同时以清胰汤浓缩后经鼻肠管注入，50 mL/次，每日2次；观察组B及观察组C分别于入院前2天，第3天给予肠内营养支持,各组均连续用药2周。比较各组治疗前后血淀粉酶及免疫指标的变化情况和住院时间、治疗总费用。结果:观察组A、B与对照组比较，差异有统计学意义(P＜0.05)。CD4+观察组A、B、C与对照组比较，差异有统计学意义(P＜0.05)；CD8+、免疫球蛋白M(immunoglobu-lin M，IgM)、免疫球蛋白G(immunoglobulin G，IgG)观察组A、B与对照组比较，差异有统计学意义(P＜0.05)；免疫球蛋白A(immunoglobulin A，IgA)观察组A与对照组比较，差异有统计学意义(P＜0.05)。结论：早期肠内营养支持联合清胰汤，可显著降低重度急性胰腺炎患者血淀粉酶，同时增加免疫力，有利于预后。
Abstract:
Objective: To compare the effects of enteral nutritional support at different time points and Qingyi Tang on immunologic factors in the patients with severe acute pancreatitis (SAP) and clinical therapeutic effects. Methods: All 92 patients were randomized into the control group, the observation groups of A, B and C according to the visiting order, 23 cases each group. The observation groups of A, B and C accepted conventional therapy, the observation group A were given enteral nutrition support at the first day of admission, simultaneously concentrated Qingyi Tang injection through nasointestinal tube, 50 mL each time, twice each day; the observation groups of B and C accepted enteral nutrition support at the second and third day of admission, and they were treated for two weeks consecutively. To compare the changes of hemodiastase and immunologic indexes, hospitalization time, total cost of treatment before and after treatment between different groups. Results: The difference had statistical meaning when the observation groups of A and B were compared with the control group (P＜0.05). The difference was statistically significant when CD4+ of the observation groups of A, B and C were compared with these of the control group (P＜0.05); The difference had statistical meaning when CD8+, IgM and IgG of the observation groups of A and B were compared with these of the control group (P＜0.05); the difference showed statistical meaning when IgA of the observation group A were compared with these of the control group (P＜0.05). Conclusion: Early enteral nutritional support at different time points and Qingyi Tang could significantly reduce hemodiastase, increase immumity ability and it is helpful for the prognosis.

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备注/Memo

备注/Memo:
收稿日期：2013-02-27作者简介：郭守强(1979—)，男，副主任医师。研究方向：外科疾病的中西医诊治。
更新日期/Last Update: 2020-04-15