[1]亓丁,李红梅,胡喜姣,等.鸦胆子有效成分抗肿瘤作用机制研究进展[J].西部中医药,2025,38(02):124-128.[doi:10.12174/j.issn.2096-9600.2025.02.27]
　QI Ding,LI Hongmei,HU Xijiao,et al.Advances in the Anti-tumor Mechanism of the Active Ingredients of Yadanzi[J].Western Journal of Traditional Chinese Medicine,2025,38(02):124-128.[doi:10.12174/j.issn.2096-9600.2025.02.27]
点击复制

鸦胆子有效成分抗肿瘤作用机制研究进展()
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
38
期数:
2025年02期
页码:
124-128
栏目:
研究进展
出版日期:
2025-02-15

文章信息/Info

Title:
Advances in the Anti-tumor Mechanism of the Active Ingredients of Yadanzi
作者:
亓丁1, 李红梅2, 胡喜姣2, 王士萌1, 刘宁1, 韩布威1, 孙秀玲3, 刘丽4
1.黑龙江中医药大学，黑龙江 哈尔滨 150036
2.黑龙江中医药大学附属第二医院，黑龙江 哈尔滨 150000
3.北大荒集团北安医院，黑龙江 北安 164000
4.黑龙江中医药大学附属第一医院，黑龙江 哈尔滨 150036
Author(s):
QI Ding1, LI Hongmei2, HU Xijiao2, WANG Shimeng1, LIU Ning1, HAN Buwei1, SUN Xiuling3, LIU Li4
1.Heilongjiang University of Traditional Chinese Medicine, Harbin 150036, China
2.The Second Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin 150000, China
3.The Beian Hospital of Beidahuang Group, Beian 164000, China
4.The First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin 150036, China
关键词:
肿瘤; 鸦胆子; 成分; 作用机制; 综述
Keywords:
tumor; ingredients; mechanism; review
分类号:
R273
DOI:
10.12174/j.issn.2096-9600.2025.02.27
文献标志码:
A
摘要:
对鸦胆子有效成分抗肿瘤相关作用机制作一综述，指出鸦胆子有效成分抗肿瘤作用机制主要包括抑制肿瘤细胞增殖、诱导细胞凋亡与自噬、调节生长周期、抑制入侵和迁移、提高放化疗敏感性等，且不同有效成分的抗肿瘤作用机制各不相同。说明鸦胆子抗肿瘤具有多靶点、多途径等特点。
Abstract:
This article summarizes the anti-tumor mechanism of the effective components of Yadanzi (Bruceae fructus), mainly including inhibition of tumor cell proliferation, induction of tumor cell apoptosis and autophagy, regulation of cell growth cycle, inhibition of tumor cell invasion and migration, and improvement of sensitivity to radiotherapy and chemotherapy, and the anti-tumor mechanism of the effective components is various, demonstrating anti-tumor effects of Yadanzi could be realized by multi-target and multi-pathway.

相似文献/References:

[1]朱建坤,王秋兰△.白花蛇舌草抗肿瘤机制研究*[J].西部中医药,2013,26(06):119.
　ZHU Jiankun,WANG Qiulan.Research on Anti-tumor Mechanism of BaiHua SheSheCao[J].Western Journal of Traditional Chinese Medicine,2013,26(02):119.
[2]徐伟,王守东△.耳穴埋籽加放松疗法对肿瘤患者睡眠质量障碍的影响[J].西部中医药,2014,27(03):115.
　XU Wei,Wang Shoudong.Effects of Ear Acupoint Pressing Method and Relax Therapy on Sleep Disorder of Cancer Patients[J].Western Journal of Traditional Chinese Medicine,2014,27(02):115.
[3]王晓荣,李湧健△,程彬彬.薯蓣皂苷元抗肿瘤作用及其机制研究[J].西部中医药,2014,27(05):140.
　WANG Xiaorong,,et al.Study on Anti-tumor Effects and the Mechanism of Diosgenin[J].Western Journal of Traditional Chinese Medicine,2014,27(02):140.
[4]王秋兰,朱建坤,韩涛,等.白花蛇舌草总黄酮对苯并(a)芘致实体瘤小鼠IL-2和IL-6的影响[J].西部中医药,2015,28(05):14.
[5]吴玮,郑慧,王天宝.某中医院429名肿瘤住院患者构成分析[J].西部中医药,2015,28(07):90.
[6]冉广宇.白杨素对结肠癌SW480细胞体内外抑制作用[J].西部中医药,2018,31(11):17.
　RAN Guangyu.The Inhibitory Effects of Chrysin on Colon Cancer SW480 Cells in Vitro and Vivo[J].Western Journal of Traditional Chinese Medicine,2018,31(02):17.
[7]尹艳芬,周晋华,李崇慧.增液承气汤对肿瘤患者口服盐酸羟考酮缓释片所致便秘的影响[J].西部中医药,2019,32(03):83.
　YIN Yanfen,ZHOU Jinhua,LI Chonghui.Effects of ZengYe ChengQi Decoction on Constipation of Cancer Patients Caused by Oral Administration of Hydroxycodone Hydrochloride Sustained Release Tablets[J].Western Journal of Traditional Chinese Medicine,2019,32(02):83.
[8]张金花,李晓娟,杨萍.隔姜灸联合耳穴压豆防治化疗后恶心呕吐[J].西部中医药,2019,32(04):109.
　ZHANG Jinhua,LI Xiaojuan,YANG Ping.Moxibustion on Ginger Combined with Auricular Pressure in the Prevention and Treatment for Nausea and Vomiting after Chemotherapy[J].Western Journal of Traditional Chinese Medicine,2019,32(02):109.
[9]苗翠影,冉光辉,王雪雁,等.结直肠癌的土家族医诊疗技法[J].西部中医药,2019,32(05):38.
　MIAO Cuiying,RAN Guanghui,WANG Xueyan,et al.Diagnostic and Therapeutic Techniques of the Tujia Ethnic Group Medicine for Colorectal Cancer[J].Western Journal of Traditional Chinese Medicine,2019,32(02):38.
[10]艾望,彭艳芳,王秀萍,等.张莹雯教授治疗肿瘤常见并发症经验总结[J].西部中医药,2020,33(02):39.[doi:10.12174/j.issn.1004-6852.2020.02.11]
　AI Wang,PENG Yanfang,WANG Xiuping,et al.Professor Zhang Yingwen′s Experience in Treating the Common Complications of Tumor[J].Western Journal of Traditional Chinese Medicine,2020,33(02):39.[doi:10.12174/j.issn.1004-6852.2020.02.11]

备注/Memo

备注/Memo:
亓丁（1995—），女，博士学位，在站博士后，主治医师。研究方向：宫颈癌的中医药防治。黑龙江省自然科学基金面上项目（H2015026）；黑龙江省博士后面上项目（LBH-Z24287）。
更新日期/Last Update: 2025-02-15