[1]姚晓兵,刘华,雷鸣.基于logistic模型探究溃疡性结肠炎肠镜下阴疮或阳疮局部望诊辨别规律[J].西部中医药,2025,38(06):56-61.[doi:10.12174/j.issn.2096-9600.2025.06.12]
　YAO Xiaobing,LIU Hua,LEI Ming.Differentiation Laws of Yin Sore or Yang Sore of Ulcerative Colitis in Local Visual Examinations under Colonoscopy Based on logistic Model[J].Western Journal of Traditional Chinese Medicine,2025,38(06):56-61.[doi:10.12174/j.issn.2096-9600.2025.06.12]
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基于logistic模型探究溃疡性结肠炎肠镜下阴疮或阳疮局部望诊辨别规律()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
38
期数:
2025年06期
页码:
56-61
栏目:
调查分析
出版日期:
2025-06-15

文章信息/Info

Title:
Differentiation Laws of Yin Sore or Yang Sore of Ulcerative Colitis in Local Visual Examinations under Colonoscopy Based on logistic Model
作者:
姚晓兵1, 刘华1, 雷鸣2
1.上海中医药大学附属岳阳中西医结合医院，上海 200437
2.上海市第七人民医院，上海 200137
Author(s):
YAO Xiaobing1, LIU Hua1, LEI Ming2
关键词:
结肠炎; 溃疡性; logistic模型; 结肠镜检查
Keywords:
colitis;  ulcerative; logistic model; colonoscopy
分类号:
R269
DOI:
10.12174/j.issn.2096-9600.2025.06.12
文献标志码:
B
摘要:
目的探究溃疡性结肠炎（ulcerative colitis，UC）阴疮、阳疮患者肠镜下黏膜形态特征。 方法选取诊断明确且经肠镜检查为UC的住院患者120例。通过住院病历资料填写UC患者临床辨证表，判别其阴、阳证型，并依据肠镜资料填写UC患者肠镜观察表，记录其黏膜形态特征。采用SPSS 25.0统计软件进行各黏膜形态特征与阴、阳证型的相关性χ2检验，将阴、阳证型与各黏膜形态特征纳入logistic回归分析模型进行分析。 结果镜下轻度黏膜粗糙呈颗粒状较无黏膜粗糙呈颗粒状，辨证为阳证的概率增加9.85倍（OR=10.85，P＜0.01）；重度黏膜粗糙呈颗粒状较无黏膜粗糙呈颗粒状，辨证为阳证的概率增加39.54倍（OR=40.54，P＜0.01）；镜下斑片状糜烂较无糜烂，辨证为阳证的概率增加12.88倍（OR=13.88，P＜0.05）；多发假性息肉辨证为阳证的概率是无息肉的0.19倍（OR=0.19，P＜0.05）。 结论若UC患者肠镜下见黏膜充血色红、黏膜表面粗糙或糜烂，则辨证为阳疮的可能性较大；若肠镜下见黏膜色淡，假性息肉形成则辨证为阴疮的可能性较大。
Abstract:
ObjectiveTo explore mucosal morphological characteristics under colonoscopy of Yin or Yang sore in ulcerative colitis (UC). MethodsThe study chose 120 inpatients with clear diagnosis, who have been diagnosed as UC via colonoscopy, clinical differentiation table for UC patients were filled up according to the inpatients’ medical records, so as to differentiate the patterns, the observation table of colonoscopy for UC patients were filled in according to the data of colonoscopy, to record the patients’ mucosal morphological characteristics. SPSS 25.0 statistical software was adopted to perform χ2 test for the correlation of mucosal morphological characteristics with Yin pattern, and Yang pattern, Yin and Yang paterns and mucosal morphological characteristics were incorporated into the logistic regression analysis model for the analysis. ResultsThe possibility of differentiated as Yang pattern increased to 9.85 times when microscopic image mild mucosal roughness and granular was compared with less mucosal roughness and granular (OR=10.85, P<0.01); the possibility of differentiated as Yang pattern increased to 39.54 times when microscopic image severe mucosal roughness and granular was compared with less mucosal roughness and granular (OR=40.54, P<0.01); the possibility of differentiated as Yang pattern increased to 12.88 times when microscopic image patchy erosion was compared with no erosion (OR=13.88, P<0.05); compared with no polyps, the possibility of differentiated as Yang pattern in multiple pseudopolyps was 0.19 times (OR=0.19, P<0.05). ConclusionMucosal congestion and redness, roughness and erosion under colonoscopy of UC can be used as the reference for syndrome differentiation of higher possibility of Yang pattern; light-colored mucosal pseudopolyps can be taken as the reference for syndrome differentiation of higher possibility of Yin pattern.

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备注/Memo

备注/Memo:
姚晓兵（1994—），男，硕士学位，主治医师。研究方向：消化系统疾病的中医药防治。上海市浦东新区卫生系统学科建设项目（PWZy2020-07）。
更新日期/Last Update: 2025-06-15