[1]梁海宁,沈涛,陈二林,等.正交试验优选萆清栓的提取工艺*[J].西部中医药,2012,25(12):20-22.
　LIANG Hai-ning,SHEN Tao,CHEN Er-lin,et al.Extraction Process of BiQing Suppository Optimized with Orthogonal Design[J].Western Journal of Traditional Chinese Medicine,2012,25(12):20-22.
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正交试验优选萆清栓的提取工艺*
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
25
期数:
2012年12期
页码:
20-22
栏目:
出版日期:
2012-12-15

文章信息/Info

Title:
Extraction Process of BiQing Suppository Optimized with Orthogonal Design
文章编号:
1004-6852(2012)12-0020-03
作者:
梁海宁，沈涛，陈二林，张宏武，王雪岩
甘肃省中医院，甘肃 兰州 730050
Author(s):
LIANG Hai-ning, SHEN Tao, CHEN Er-lin, ZHANG Hong-wu, WANG Xue-yan
Gansu Province Hospital of Traditional Chinese Medicine, Lanzhou 730050, China
关键词:
萆清栓; 正交试验; 提取工艺; 盐酸小檗碱
Keywords:
BiQing suppository;  orthogonal design;  extraction process;  berberine hydrochloride
分类号:
R284.2
文献标志码:
A
摘要:
目的：优选萆清栓提取工艺。方法：以水为提取溶剂，药液比、提取时间、提取次数为考察因素，以出膏率及盐酸小檗碱含量为评价指标，采用正交试验优化提取工艺。结果：最佳提取工艺为用 10 倍量水， 1.5 h/ 次，提取 2 次。结论：所选择的工艺稳定可行，可用于萆清栓的工业生产。
Abstract:
Objective: To optimize extraction process of BiQing suppository. Method: Extraction process was optimized with orthogonal design by taking water as extraction solvent, drug-liquid ratio, extracting time and times as the indexes, the extraction rate and content of berberine hydrochloride as evaluating indicators. Result: the optimal extraction was using ten folds amount of water, reflux extraction twice, once 1.5 hours. Conclusion: The extraction process is stable and could be used to the production of BiQingShuang.

参考文献/References:

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备注/Memo

备注/Memo:
收稿日期：2012-06-27 * 基金项目：兰州市科技发展计划项目(编号 2011-ZD-15) 作者简介：梁海宁(1974—)，女，主管中药师。研究方向：中药制剂的研发。
更新日期/Last Update: 1900-01-01