[1]李伟伟,王鸣池,于盼盼,等.奥拉西坦联合三七通舒治疗血管性痴呆的临床疗效观察[J].西部中医药,2013,26(02):81-83.
　LI Weiwei,WANG Mingchi,YU Panpan,et al.Observation on Clinical Effects of Oxiracetam Capsule and SanQi TongShu Capsule in Treating Vascular Dementia[J].Western Journal of Traditional Chinese Medicine,2013,26(02):81-83.
点击复制

奥拉西坦联合三七通舒治疗血管性痴呆的临床疗效观察
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年02期
页码:
81-83
栏目:
报道·衷中参西
出版日期:
2013-02-15

文章信息/Info

Title:
Observation on Clinical Effects of Oxiracetam Capsule and SanQi TongShu Capsule in Treating Vascular Dementia
文章编号:
1004-6852(2013)02-0081-03
作者:
李伟伟1; 王鸣池2; 于盼盼1; 王悦1
1 天津中医药大学，天津 300037；2 天津市南开医院
Author(s):
LI Weiwei1;  WANG Mingchi2;  YU Panpan1;  WANG Yue1
1 Tianjin University of Traditional Chinese Medicine, Tianjin 300037, China; 2 Tianjin Municipality Nankai Hospital
关键词:
血管性痴呆; 奥拉西坦胶囊; 三七通舒胶囊; 临床疗效
Keywords:
vascular dementia;  oxiracetam capsule;  SanQi TongShu capsule;  clinical effects
分类号:
R749.13
文献标志码:
B
摘要:
目的：观察奥拉西坦联合三七通舒治疗血管性痴呆的临床疗效。方法：将60例血管性痴呆患者随机分为治疗组和对照组各30例，对照组给予奥拉西坦胶囊0.8g/次，3次/d，口服，治疗组在对照组治疗的基础上加用三七通舒胶囊0.2g/次，3次/d，口服，疗程均为12周。计算治疗前、后Flstein简易精神状态检查量表(MMSE)、临床痴呆程度量表(CDR)、日常生活评定量表(ADL)、神经功能缺损量表(NIHSS)评分。结果：治疗前2组各项指标评分比较差异无统计学意义(P＞0.05)，治疗前后及治疗后2组各项指标评分比较差异有统计学意义(P＜0.05)。结论：奥拉西坦联合三七通舒能明显改善血管性痴呆患者的认知功能，提高日常生活能力，改善神经损伤。
Abstract:
Objective: To observe clinical effects of oxiracetam capsule and SanQi TongShu capsule in treating vascular dementia. Method: Sixty patients were randomly divided into the treatment group and the control group equally. The control group took oxiracetam capsule, 0.8g each time, three times each day. Based on the treatment given to the control group, the treatment group also took SanQi TongShu capsule, 0.2g each time, three times each day.One course of treatment was 12 weeks. The scales of MMSE, CDR, ADL and NIHSS were calculated before and after treating. Result: The differences of comparisons between both groups before treating had no statistical meaning in indicators (P>0.05). The differences of comparisons between both groups demonstrated statistical meaning in indexes before and after treating (P＜0.05). Conclusion: Oxiracetam capsule and SanQi TongShu capsule could improve cognitive function, activity of daily living and nerve damage of patients with vascular dementia.

参考文献/References:

［1］ 谢建平，吴承龙，孙新芳.安理申联合克林澳治疗早期血管性痴呆的临床研究［J］.重庆医学，2008,37(5)：498-499. ［2］ American Psychiatric Association.Diagnostic and statistcal manul of mental disorders (DSM-IV)［M］.4thnd washington American：Psychiatric Association，1994：143-147. ［3］ Newman MF，Kirchner JL，Phillips-Bute B，et al.Longitudinal assessment of neurocognitive functions after coronary-artery bypass surgery［J］.N Engl J Med，2001，344(6)：395-402. ［4］ 刘江萍，龙全铭.脑白质疏松与血管性痴呆的相关因素分析［J］.贵州医药，2004，28(7)：596-599. ［5］ 王体强，徐楠，王浴生.新型益智药奥拉西坦的药理与临床应用进展［J］.四川生理科学杂志，2002，24(2)：145-148. ［6］ 朱敏姿，徐彬.三七通舒胶囊在急性缺血性脑卒中治疗中的应用［J］.浙江中医杂志，2009，44(11)：854-855.

相似文献/References:

[1]高晓兰,朱增强,陈彦文,等.当归补血汤加味对血管性痴呆大鼠的脑保护作用研究[J].西部中医药,2013,26(04):22.
　GAO Xiaolan,ZHU Zengqiang,CHEN Yanwen,et al.Study on Modified DangGui BuXueTang to Cerebral Protection of Rats with Vascular Dementia[J].Western Journal of Traditional Chinese Medicine,2013,26(02):22.
[2]王保平,张圆,陈怡名,等.龙首参葛丸对血管性痴呆大鼠海马CA1区组织结构变化的影响[J].西部中医药,2019,32(06):6.
　WANG Baoping,ZHANG Yuan,CHEN Yiming,et al.Impact of LongShou ShenGe Pills on the Structural Changes of the Tissue in Hippocampal CAI Region of the Rat with Vascular Dementia[J].Western Journal of Traditional Chinese Medicine,2019,32(02):6.
[3]郭铁,雷励△,程平荣,等.补肾活血片治疗血管性痴呆60例[J].西部中医药,2019,32(06):75.
　GUO Tie,LEI Li,CHENG Pingrong,et al.Treatment for 60 Cases of Vascular Dementia by Kidney-invigorating Blood-activating Tablets[J].Western Journal of Traditional Chinese Medicine,2019,32(02):75.
[4]张慧,张婷,陈锐,等.醒脑方对血管性痴呆大鼠脑组织学习记忆能力的保护作用[J].西部中医药,2020,33(07):20.[doi:10.12174/j.issn.1004-6852.2020.07.05]
　ZHANG Hui,ZHANG Ting,et al.Protective Effects of Xingnao Prescription on Learning and Memory Ability of Brain Tissue in VD Rats[J].Western Journal of Traditional Chinese Medicine,2020,33(02):20.[doi:10.12174/j.issn.1004-6852.2020.07.05]
[5]陈业文,陈炜,吴林,等.基于肠道微生物探讨从脾胃论治血管性痴呆[J].西部中医药,2021,34(04):145.[doi:10.12174/j.issn.2096-9600.2021.04.36]
　CHEN Yewen,CHEN Wei,WU Lin,et al.Discussion on Treating Vascular Dementia from Spleen and Stomach Based on Intestinal Microorganism[J].Western Journal of Traditional Chinese Medicine,2021,34(02):145.[doi:10.12174/j.issn.2096-9600.2021.04.36]
[6]孟胜喜,付剑亮,霍清萍,等.恒清Ⅰ号方联合盐酸多奈哌齐对血管性痴呆患者的作用及其机制研究[J].西部中医药,2021,34(01):1.[doi:10.12174/j.issn.2096-9600.2021.01.01]
　MENG Shengxi,FU Jianliang,HUO Qingping,et al.Study on the Effects of Hengqing Prescription No.1 and Donepezil Hydrochloride on Vascular Dementia and Its Mechanism[J].Western Journal of Traditional Chinese Medicine,2021,34(02):1.[doi:10.12174/j.issn.2096-9600.2021.01.01]
[7]陈静,陈炜,唐秀松,等.基于网络药理学探讨丹参治疗血管性痴呆的作用机制[J].西部中医药,2022,35(11):22.[doi:10.12174/j.issn.2096-9600.2022.11.05]
　CHEN Jing,CHEN Wei,TANG Xiusong,et al.Discussion on the Mechanism of Danshen in the Treatment of Vascular Dementia Based on Network Pharmacology[J].Western Journal of Traditional Chinese Medicine,2022,35(02):22.[doi:10.12174/j.issn.2096-9600.2022.11.05]

备注/Memo

备注/Memo:
收稿日期：2012-09-15 作者简介：李伟伟(1986—)，男，硕士研究生。研究方向：脑血管病及微创神经外科。
更新日期/Last Update: 2013-02-15