[1]卢健敏.温肺止流丹对变应性鼻炎大鼠免疫调节作用机制的研究[J].西部中医药,2013,26(07):26-27.
　LU Jianmin.Research of WenFei ZhiLiuDan on Immunoregulation Mechanism of Rats with Allergic Rhinitis[J].Western Journal of Traditional Chinese Medicine,2013,26(07):26-27.
点击复制

温肺止流丹对变应性鼻炎大鼠免疫调节作用机制的研究
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年07期
页码:
26-27
栏目:
方药·药理研究
出版日期:
2013-07-15

文章信息/Info

Title:
Research of WenFei ZhiLiuDan on Immunoregulation Mechanism of Rats with Allergic Rhinitis
文章编号:
1004-6852(2013)07-0026-02
作者:
卢健敏
泉州医学高等专科学校，福建 泉州 362000
Author(s):
LU Jianmin
Quanzhou Medical College, Quanzhou 362000, China
关键词:
温肺止流丹; 变应性鼻炎; 白细胞介素4; 血清中嗜酸粒细胞阳离子
Keywords:
WenFei ZhiLiuDan;  allergic rhinitis;  IL-4;  ECP
分类号:
R765.21
文献标志码:
A
摘要:
目的：观察温肺止流丹对肺气虚型变态反应性鼻炎(AR)大鼠模型血清中嗜酸粒细胞阳离子(ECP)、白细胞介素4(IL-4)的影响，探讨其治疗变应性鼻炎的机制。方法：采用病证结合的方法造模，用ELISA法检测大鼠血清ECP、IL-4的含量。结果：温肺止流丹能够降低实验性AR大鼠血清IL-4、ECP的含量。结论：温肺止流丹可能通过降低大鼠血清IL-4、ECP水平，对实验性AR大鼠发挥治疗作用。
Abstract:
Objective: To observe the effects of WenFei ZhiLiuDan on serum ECP and IL-4 of the rats with allergic rhinitis (AR) of lung-Qi deficiency pattern, and explore its mechanism for allergic rhinitis. Method: The rat models were made with the method of combined with disease and syndrome, and the contents of ECP and IL-4 in rats were detected with ELISA method. Result: WenFei ZhiLiuDan could decrease the contents of IL-4 and ECP of experimental rats with AR. Conclusion: WenFei ZhiLiuDan are effective in treating rats with AR which might be through lowering the levels of IL-4 and ECP of the rats.

相似文献/References:

[1]张德骞.自拟通窍止鼽汤联合西替利嗪治疗变应性鼻炎的疗效及对TNF-α和IL-4水平的影响[J].西部中医药,2015,28(05):28.
[2]季红健,王东方.变应性鼻炎中医辨证分型与ECP的相关性研究[J].西部中医药,2013,26(05):127.
　JI Hongjian,WANG Dongfang.Correlation Study between ECP and Syndrome Differentiation of Allergic Rhinitis[J].Western Journal of Traditional Chinese Medicine,2013,26(07):127.
[3]谢强,指导：付文洋.变应性鼻炎中医治疗研究现状[J].西部中医药,2015,28(03):140.
[4]付文洋,马甜甜,曾萍萍,等.鼻鼽的分期论治研究[J].西部中医药,2020,33(03):66.[doi:10.12174/j.issn.1004-6852.2020.03.18]
　FU Wenyang,MA Tiantian,ZENG Pingping,et al.Research on Phased Therapy of Allergic Rhinitis[J].Western Journal of Traditional Chinese Medicine,2020,33(07):66.[doi:10.12174/j.issn.1004-6852.2020.03.18]
[5]吴小秦,王翔,符国庆,等.温肺健脾方治疗肺脾虚寒型变应性鼻炎91例[J].西部中医药,2021,34(12):84.[doi:10.12174/j.issn.2096-9600.2021.12.22]
　WU Xiaoqin,WANG Xiang,FU Guoqing,et al.Lung-warming Spleen-invigorating Prescription in Treating 91 Patients with Allergic Rhinitis of Lung and Spleen Deficiency-cold Pattern[J].Western Journal of Traditional Chinese Medicine,2021,34(07):84.[doi:10.12174/j.issn.2096-9600.2021.12.22]

备注/Memo

备注/Memo:
收稿日期：2012-12-25 作者简介：卢健敏(1976—)，女，硕士学位，讲师，主治医师。研究方向：中医药基础及临床研究。
更新日期/Last Update: 2013-07-15