[1]卢健敏.温肺止流丹对变应性鼻炎大鼠免疫调节作用机制的研究[J].西部中医药,2013,26(07):26-27.
 LU Jianmin.Research of WenFei ZhiLiuDan on Immunoregulation Mechanism of Rats with Allergic Rhinitis[J].Western Journal of Traditional Chinese Medicine,2013,26(07):26-27.
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温肺止流丹对变应性鼻炎大鼠免疫调节作用机制的研究
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
26
期数:
2013年07期
页码:
26-27
栏目:
方药·药理研究
出版日期:
2013-07-15

文章信息/Info

Title:
Research of WenFei ZhiLiuDan on Immunoregulation Mechanism of Rats with Allergic Rhinitis
文章编号:
1004-6852(2013)07-0026-02
作者:
卢健敏
泉州医学高等专科学校,福建 泉州 362000
Author(s):
LU Jianmin
Quanzhou Medical College, Quanzhou 362000, China
关键词:
温肺止流丹变应性鼻炎白细胞介素4血清中嗜酸粒细胞阳离子
Keywords:
WenFei ZhiLiuDan allergic rhinitis IL-4 ECP
分类号:
R765.21
文献标志码:
A
摘要:
目的:观察温肺止流丹对肺气虚型变态反应性鼻炎(AR)大鼠模型血清中嗜酸粒细胞阳离子(ECP)、白细胞介素4(IL-4)的影响,探讨其治疗变应性鼻炎的机制。方法:采用病证结合的方法造模,用ELISA法检测大鼠血清ECP、IL-4的含量。结果:温肺止流丹能够降低实验性AR大鼠血清IL-4、ECP的含量。结论:温肺止流丹可能通过降低大鼠血清IL-4、ECP水平,对实验性AR大鼠发挥治疗作用。
Abstract:
Objective: To observe the effects of WenFei ZhiLiuDan on serum ECP and IL-4 of the rats with allergic rhinitis (AR) of lung-Qi deficiency pattern, and explore its mechanism for allergic rhinitis. Method: The rat models were made with the method of combined with disease and syndrome, and the contents of ECP and IL-4 in rats were detected with ELISA method. Result: WenFei ZhiLiuDan could decrease the contents of IL-4 and ECP of experimental rats with AR. Conclusion: WenFei ZhiLiuDan are effective in treating rats with AR which might be through lowering the levels of IL-4 and ECP of the rats.

相似文献/References:

[1]季红健,王东方.变应性鼻炎中医辨证分型与ECP的相关性研究[J].西部中医药,2013,26(05):127.
 JI Hongjian,WANG Dongfang.Correlation Study between ECP and Syndrome Differentiation of Allergic Rhinitis[J].Western Journal of Traditional Chinese Medicine,2013,26(07):127.
[2]谢强,指导:付文洋.变应性鼻炎中医治疗研究现状[J].西部中医药,2015,28(03):140.
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[5]吴小秦,王翔,符国庆,等.温肺健脾方治疗肺脾虚寒型变应性鼻炎91例[J].西部中医药,2021,34(12):84.[doi:10.12174/j.issn.2096-9600.2021.12.22]
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备注/Memo

备注/Memo:
收稿日期:2012-12-25 作者简介:卢健敏(1976—),女,硕士学位,讲师,主治医师。研究方向:中医药基础及临床研究。
更新日期/Last Update: 2013-07-15