[1]刘圳奋,马红霞,李秀宁,等.痛风性关节炎与高尿酸血症炎性细胞因子水平比较[J].西部中医药,2014,27(08):157-158.
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痛风性关节炎与高尿酸血症炎性细胞因子水平比较
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年08期
页码:
157-158
栏目:
出版日期:
2014-08-15

文章信息/Info

文章编号:
1004-6852(2014)08-0028-03
作者:
刘圳奋马红霞李秀宁路 婷王丽红王彩霞
兰州市第一人民医院综合内科,甘肃 兰州 730050
关键词:
痛风高尿酸血症肿瘤坏死因子白细胞介素-1白细胞介素-6
分类号:
R971+1
摘要:
目的:观察痛风性关节炎和高尿酸血症患者肿瘤坏死因子α(TNF-α)、白细胞介素-1(IL-1)和白细胞介素-6(IL-6)等炎性细胞因子的血清水平。方法:分别测定41例痛风性关节炎患者(痛风组)、52例高尿酸血症患者(高尿酸组)和30例健康体检者(对照组)3组人群TNF-α、IL-1和IL-6等细胞因子血清水平。结果:TNF-α、IL-1和IL-6痛风组明显高于高尿酸组、对照组(P<0.05)。TNF-α、IL-1高尿酸组与对照组无明显差异(P>0.05),IL-6高尿酸组高于对照组(P<0.05)。结论:炎性细胞因子在痛风性关节炎患者的发病过程中起到了重要作用,而无症状的高尿酸血症患者炎性细胞因子还未达到导致炎症的水平。

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备注/Memo

备注/Memo:
作者简介:刘圳奋(1963—),男,主任医师。研究方向:心血管疾病的诊治。
更新日期/Last Update: 2014-08-15