[1]高万飞,徐厚谦,金华.中医治法对高尿酸血症大鼠模型AngⅠ,AngⅡ水平的影响[J].西部中医药,2015,28(05):22-24.
点击复制

中医治法对高尿酸血症大鼠模型AngⅠ,AngⅡ水平的影响
分享到:

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
28
期数:
2015年05期
页码:
22-24
栏目:
方药·药理研究
出版日期:
2015-05-15

文章信息/Info

文章编号:
1004-6852(2015)05-0022-03
作者:
高万飞1徐厚谦2金华2
1 武威职业学院中医康复技术系,甘肃 武威733000; 2 甘肃中医学院中医内科教研室
关键词:
高尿酸血症大鼠AngⅠAngⅡ中医治法
分类号:
R259.8
文献标志码:
A
摘要:
目的:探讨不同中医治法对高尿酸血症模型大鼠血清AngⅠ,AngⅡ水平的影响。方法:将Wistar大鼠135只随机分为空白对照组、模型组、西药治疗组与中药复方(滋肾阴、温肾阳、健脾、活血、化痰及利湿组,每组15只)6个治疗组,除空白对照组外,其余各组采用腺嘌呤联合乙胺丁醇法建立大鼠高尿酸血症动物模型,造模第21天开始给予各治疗组相应治疗,连续2周。检测血清AngⅠ,AngⅡ水平,观察其变化情况。结果:与模型组比较,除西药治疗组与活血组、利湿组和化痰组血清AngⅠ水平降低外其余治疗组血清AngⅠ水平变化不明显,无显著性差异(P>0.05);西药治疗组与治疗组中的活血组、利湿组和化痰组血清AngⅡ水平明显下降,有显著性差异(P<0.05)。结论:活血、利湿和化痰治法有降低血清AngⅠ水平的趋势;不同中医治法均可降低血清AngⅡ水平,其中以活血、利湿、化痰法治疗效果明显,对高尿酸血症具有治疗作用。

相似文献/References:

[1]覃仕化,汪悦.痹痛灵颗粒对胶原诱导性关节炎大鼠血清及滑膜组织匀浆中IL-2的影响[J].西部中医药,2011,24(11):9.
[2]陈进凡,刘媛,柳渊洁,等.肠毒清口服液对全身炎症反应综合征大鼠体质量及进食量的影响[J].西部中医药,2011,24(11):10.
[3]董敏,瞿东晖,杨雪萍,等.产益康栓对大鼠阴道黏膜刺激及过敏反应的实验研究[J].西部中医药,2013,26(03):19.
 DONG Min,QU Donghui,YANG Xueping,et al.Experimental Study of the Effects of ChanY iKang Suppository on the Irritation and Allergy of Vaginal Mucosa in Rats[J].Western Journal of Traditional Chinese Medicine,2013,26(05):19.
[4]寇宁,张玉香,王一强,等.温肾胶囊对抑郁大鼠模型性功能的影响[J].西部中医药,2013,26(05):12.
 KOU Ning,ZHANG Yuxiang,WANG Yiqiang,et al.Effects of W enShen Capsule on Sexual Function of Depressed Rat Model[J].Western Journal of Traditional Chinese Medicine,2013,26(05):12.
[5]高晓兰,朱增强,陈彦文,等.当归补血汤加味对血管性痴呆大鼠的脑保护作用研究[J].西部中医药,2013,26(04):22.
 GAO Xiaolan,ZHU Zengqiang,CHEN Yanwen,et al.Study on Modified DangGui BuXueTang to Cerebral Protection of Rats with Vascular Dementia[J].Western Journal of Traditional Chinese Medicine,2013,26(05):22.
[6]王春爱,王迎斌,贾国龙,等.豆腐果苷对大鼠坐骨神经压迫性模型机械痛敏和热痛敏的影响[J].西部中医药,2012,25(07):20.
 WANG Chun-ai,WANG Ying-Bin,JIA Guo-long,et al.The Effect of Helicid on MWT and TWL in Rat Model with Chronic Compression Injury of Sciatic Nerve[J].Western Journal of Traditional Chinese Medicine,2012,25(05):20.
[7]龚云,王超,亢建国.运动结合灵芝多糖干预对糖尿病大鼠血脂的影响[J].西部中医药,2013,26(08):8.
 GONG Yun,WANG Chao,KANG Jianguo.Effects of Exercise and Ganoderan Intervention on Blood Fat of Rats with Diabetes Mellitus[J].Western Journal of Traditional Chinese Medicine,2013,26(05):8.
[8]贡布东智,阿召,何强,等.藏药“五味麝香丸”药效学实验研究[J].西部中医药,2013,26(08):55.
 GONGBU Dongzhi,A Zhao,HE Qiang,et al.Experimental Study on the Pharmacodynamics of Tibetan Drug “WuWei SheXiang Pill"[J].Western Journal of Traditional Chinese Medicine,2013,26(05):55.
[9]侯建平,王亚军,严亚峰,等.虎杖提取物抗动物高尿酸血症的实验研究[J].西部中医药,2012,25(05):21.
 HOU Jian-ping,WANG Ya-jun,YAN Ya-feng,et al.Study of Polygonum Cuspidatum Extract on Anti-Hyperuricemia in Rats and Mice[J].Western Journal of Traditional Chinese Medicine,2012,25(05):21.
[10]吴丽萍,李玉霞,尚菁,等.知柏地黄丸对性早熟模型大鼠FSH、T水平的影响*[J].西部中医药,2013,26(11):10.
 WU Liping,LI Yuxia,SHANG Jing,et al.Action of ZhiBai DiHuang Pill on the Levels of FSH and T of Rats with Sexual Precocity[J].Western Journal of Traditional Chinese Medicine,2013,26(05):10.

备注/Memo

备注/Memo:
作者简介:高万飞(1977—),男,硕士学位,讲师。研究方向:中医教学与临床。
更新日期/Last Update: 2015-05-15