[1]石洲宝,陈长浩,高娜,等.安神二号胶囊对慢性精神分裂症患者认知和社会功能的影响[J].西部中医药,2015,28(04):1-3.
点击复制

安神二号胶囊对慢性精神分裂症患者认知和社会功能的影响
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
28
期数:
2015年04期
页码:
1-3
栏目:
出版日期:
2015-04-15

文章信息/Info

文章编号:
1004-6852(2015)04-0001-03
作者:
石洲宝，陈长浩，高娜，刘成松，刘敏科，黄生辉
甘肃中医学院附属医院，甘肃 兰州 730020
关键词:
精神分裂症; 慢性; 安神胶囊; 维思通; 认知; 社会功能
分类号:
R749.3
文献标志码:
A
摘要:
目的：探讨安神胶囊对慢性精神分裂症患者认知和社会功能的影响。方法：采用随机、双盲、双模拟试验方法，将200例患者随机分为观察组和对照组各100例，观察组口服安神胶囊，4粒/次，3次/d；对照组口服维思通，1～1.5 mg/d，2组均治疗8周。于基线和治疗8周末分别计算认知功能评定量表（WCST）评分、社会功能量表（SDSS)评分；于治疗前，治疗第2、4、6、8周分别计算阳性症状量表（SAPS）评分、阴性症状量表（SANS）评分、临床总体印象量表（CGI）评分，并以药物副反应量表（TESS)评定药物的副反应。结果：治疗第8周末，2组SAPS、SANS及SDSS评分均较基线降低，WCST指标中除了观察组持续应答数外均获改善，差异均有统计学意义（P＜0.05）；观察组SANS、SAPS评分的降低较对照组更为明显（P＜0.05)。安神胶囊组WCST各指标改善较对照组明显（P＜0.05)。SANA有效率、CGI临床进步率观察组分别为79.9%、86.6%，对照组分别为85.3%、89.3%,2组比较差异均无统计学意义（P＞0.05)。结论：安神胶囊对慢性精神分裂症患者认知和社会功能的改善更为有效，且副反应小。

相似文献/References:

[1]马军,郑月萍,严兴海,等.加味薏苡附子败酱散治疗寒湿血瘀型慢性前列腺炎38例临床研究[J].西部中医药,2012,25(12):7.
　MA Jun,ZHENG Yue-ping,YAN Xing-hai,et al.On Modified YiYi FuZi BaiJiangSan for 38 Cases of Chronic Prostatitis of Cold-dampness Blood Stasis Pattern[J].Western Journal of Traditional Chinese Medicine,2012,25(04):7.
[2]孙安兵,王三吉,金芃.麻杏甘石汤合瓜蒌薤白桂枝汤治疗老年慢性喘证122例临床观察[J].西部中医药,2012,25(12):71.
　SUN An-bing,WANG San-ji,JIN Peng.Clinical Observation on MaXing GanShiTang and GuaLou XieBai GuiZhiTang for 122 Cases of Senile Chronic Asthma[J].Western Journal of Traditional Chinese Medicine,2012,25(04):71.
[3]崔毅.益气活血汤治疗慢性盆腔炎64例临床观察[J].西部中医药,2012,25(12):75.
　CUI Yi.Clinical Observation on YiQi HuoXueTang and Activating Blood Decoction in Treating 64 Cases of Chronic Pelvic Inflammatory Disease[J].Western Journal of Traditional Chinese Medicine,2012,25(04):75.
[4]应语,姚昶△,卞卫和,等.生肌玉红膏干预下肢慢性溃疡创面炎症反应的临床研究*[J].西部中医药,2013,26(02):7.
　YING Yu,YAO Chang,BIAN Weihe,et al.Clinical Study on Intervention of ShengJi YuHongGao to Wound Inflammatory Reaction of Leg with Chronic Ulcer[J].Western Journal of Traditional Chinese Medicine,2013,26(04):7.
[5]樊斗霜.枳实消痞丸(汤)合丹参饮加减治疗慢性萎缩性胃炎32例[J].西部中医药,2013,26(02):72.
　FAN Doushuang.Modified ZhiShi XiaoPiWan(Prescription) and DanShenYin in Treating 32 Cases of Chronic Atrophic Gastritis[J].Western Journal of Traditional Chinese Medicine,2013,26(04):72.
[6]关亚珍,指导：张洪涛.矩阵针灸治疗脾虚型慢性腹泻 30 例临床观察[J].西部中医药,2013,26(03):62.
　GUAN Yazhen Director: ZHANG Hongtao.Matrix Acupuncture in Treating 30 Cases of Chronic Diarrhea of Spleen Deficiency Pattern[J].Western Journal of Traditional Chinese Medicine,2013,26(04):62.
[7]尤海鹰.制萎煎治疗脾胃虚弱型慢性萎缩性胃炎40例[J].西部中医药,2013,26(03):84.
　YOU Haiying.ZhiWeiJian in Treating 40 Cases of Chronic Atrophic Gastritis of Spleen-stomach Deficiency Pattern[J].Western Journal of Traditional Chinese Medicine,2013,26(04):84.
[8]张建平,刘洁,赵志亮.针灸治疗慢性前列腺炎25例疗效观察[J].西部中医药,2013,26(03):111.
　ZHANG Jianping,LIU Jie,ZHAO Zhiliang.Observation on Acupuncture in Treating 25 Cases of Chronic Prostatitis[J].Western Journal of Traditional Chinese Medicine,2013,26(04):111.
[9]孙国荣,景克荣,权亚喜.生脉注射液对慢性心衰患者心功能及其心率变异性的影响[J].西部中医药,2013,26(04):68.
　SUN Guorong,JING Kerong,QUAN Yaxi.The Influence of ShengMai Injection on Heart Function and Heart Rate Variability of Patients with Chronic Heart Failure[J].Western Journal of Traditional Chinese Medicine,2013,26(04):68.
[10]陈强,王进吉,王亨飞,等.小针刀治疗慢性扁桃体炎43例[J].西部中医药,2013,26(04):71.
　CHEN Qiang,WANG Jingji,WANG Hengfei,et al.Treating 43 Cases of Chronic Tonsillitis with Small Needle-knife[J].Western Journal of Traditional Chinese Medicine,2013,26(04):71.
[11]张永国,郭晓娟△.中药汤剂联合阿立哌唑治疗慢性精神分裂症59例[J].西部中医药,2017,30(12):88.
　ZHANG Yonguo,GUO Xiaojuan.Herbal Decoction Combined with Aripiprazole in Treating 59 Cases of Chronic Schizophrenia[J].Western Journal of Traditional Chinese Medicine,2017,30(04):88.
[12]杨兰,冯玉霞,宁静,等.经颅磁刺激联合康复训练对慢性精神分裂症患者阴性症状的影响[J].西部中医药,2022,35(07):106.[doi:10.12174/j.issn.2096-9600.2022.07.28]
　YANG Lan,FENG Yuxia,NING Jing,et al.Effects of Transcranial Magnetic Stimulation Combined with Rehabilitation Training on Negative Symptoms in Patients with Chronic Schizophrenia[J].Western Journal of Traditional Chinese Medicine,2022,35(04):106.[doi:10.12174/j.issn.2096-9600.2022.07.28]

备注/Memo

备注/Memo:
*基金项目：甘肃省中医药科研项目（编号GZK-2013-33）。作者简介：石洲宝(1965—)，男，硕士研究生导师，副主任医师。研究方向：精神（心理）障碍的临床诊治。
更新日期/Last Update: 2015-04-15