[1]叶佩燕,苗慧,杨宗国,等.解毒逐瘀方保留灌肠治疗早中期慢性重型肝炎患者的临床观察[J].西部中医药,2012,25(07):1-3.
　YE Pei-yan,MIAO Hui,YANG Zong-guo,et al.Clinical Observation on Chronic Severe Hepatitis at Early-Middle Stage Treated with Retention Enema of JieDu ZhuYuFang[J].Western Journal of Traditional Chinese Medicine,2012,25(07):1-3.
点击复制

解毒逐瘀方保留灌肠治疗早中期慢性重型肝炎患者的临床观察
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
25
期数:
2012年07期
页码:
1-3
栏目:
出版日期:
2012-07-15

文章信息/Info

Title:
Clinical Observation on Chronic Severe Hepatitis at Early-Middle Stage Treated with Retention Enema of JieDu ZhuYuFang
文章编号:
1004-6852(2012)07-0001-03
作者:
叶佩燕，苗慧，杨宗国，陈晓蓉△，陆云飞，刘成
上海市（复旦大学附属）公共卫生临床中心，上海 201508
Author(s):
YE Pei-yan, MIAO Hui, YANG Zong-guo, CHEN Xiao-rong△, LU Yun-fei, LIU Cheng,
Shanghai Public Health Clinical Center (Affiliated to Fudan University), Shanghai 201508, China
关键词:
肝炎; 慢性; 重型; 解毒逐瘀方; 早中期; 保留灌肠
Keywords:
hepatitis;  chronic;  severe;  JieDu ZhuYuFang;  at early and middle stage;  retention enema
分类号:
R575.1
文献标志码:
A
摘要:
目的：观察解毒逐瘀方治疗早中期慢性重型肝炎（chronic severe hepatitis,CSH）的临床疗效。方法：将79例早中期CSH患者根据是否接受中药灌肠分为灌肠组31例，对照组48例。对照组以常规西药治疗；灌肠组常规西药口服联合解毒逐瘀方100 mL灌肠治疗，1次/d。观察患者肝功能、凝血功能变化及并发症、生存率情况。结果：灌肠组可降低早中期CSH患者ALT、AST、TBiL、DBiL水平，提高总胆固醇含量（P＜0.05）；与对照组相比，灌肠组对ALT、AST、DBiL及TC的改善程度更为显著（P＜0.05）。灌肠组可显著缩短早中期CSH患者凝血酶原时间，提高凝血酶原活动度（P＜0.05）；与对照组相比，灌肠组改善程度更为显著（P＜0.05）。灌肠组可有效减少早中期CSH患者并发症，提高生存率，与对照组相比，差异有统计学意义（P＜0.05）。结论：解毒逐瘀方可有效改善早中期CSH患者肝功能及凝血功能，减少并发症发生，提高生存率，临床疗效较好。
Abstract:
Objective: To observe clinical effects of JieDu ZhuYuFang in treating chronic severe hepatitis at early and middle stage. Method: A total of 79 patients were divided into 31 cases in enema group and 48 cases in control group according to receiving enema or not. Control group received routine western medicine; enema group received routine western medicine and retention enema with 100 ml of JieDu ZhuYuFang, once per day. Liver function, blood coagulation function, complication and survival rates of patients were observed. Result: ALT, AST, TBiL and DBiL of patients in enema group decreased, content of total cholesterol increased (P＜0.05); compared with control group, enema group improved more greatly in ALT, AST, DBiL and TC (P＜0.05). Time of prothrombin shortened notably in enema group and the activity improved (P＜0.05); enema group improved significantly compared with compared with control group(P＜0.05). Complications of patients in enema group decreased, survival rate improved, comparison with control group showed statistical meaning (P＜0.05). Conclusion: JieDu ZhuYuFang can effectively improve liver function and coagulation of patients with chronic severe hepatitis at early and middle stage with better clinical effects, decrease complication and raise survival rate.

相似文献/References:

[1]崔毅.益气活血汤治疗慢性盆腔炎64例临床观察[J].西部中医药,2012,25(12):75.
　CUI Yi.Clinical Observation on YiQi HuoXueTang and Activating Blood Decoction in Treating 64 Cases of Chronic Pelvic Inflammatory Disease[J].Western Journal of Traditional Chinese Medicine,2012,25(07):75.
[2]樊斗霜.枳实消痞丸(汤)合丹参饮加减治疗慢性萎缩性胃炎32例[J].西部中医药,2013,26(02):72.
　FAN Doushuang.Modified ZhiShi XiaoPiWan(Prescription) and DanShenYin in Treating 32 Cases of Chronic Atrophic Gastritis[J].Western Journal of Traditional Chinese Medicine,2013,26(07):72.
[3]尤海鹰.制萎煎治疗脾胃虚弱型慢性萎缩性胃炎40例[J].西部中医药,2013,26(03):84.
　YOU Haiying.ZhiWeiJian in Treating 40 Cases of Chronic Atrophic Gastritis of Spleen-stomach Deficiency Pattern[J].Western Journal of Traditional Chinese Medicine,2013,26(07):84.
[4]张建平,刘洁,赵志亮.针灸治疗慢性前列腺炎25例疗效观察[J].西部中医药,2013,26(03):111.
　ZHANG Jianping,LIU Jie,ZHAO Zhiliang.Observation on Acupuncture in Treating 25 Cases of Chronic Prostatitis[J].Western Journal of Traditional Chinese Medicine,2013,26(07):111.
[5]魏国俊,郑恒恒,指导：燕中.损伤胶囊与正骨水治疗慢性软组织损伤疗效比较[J].西部中医药,2013,26(11):8.
　WEI Guojun,ZHENG Hengheng,Director: YAN Zhong.The Difference in Clinical Effects between SunShang Capsule and Bonesetting Liquid in Treating Chronic Soft Tissue Injury[J].Western Journal of Traditional Chinese Medicine,2013,26(07):8.
[6]朱建坤,温晓辉,梁玉杰△.敦煌葆元膏对下丘脑-垂体-肾上腺轴作用的实验研究*[J].西部中医药,2013,26(11):13.
　ZHU Jiankun,WEN Xiaohui,LIANG Yujie.Experimental Study on the Effects of DunHuang BaoYuan Ointment on Hypothalamic-pituitary-adrenal Axis[J].Western Journal of Traditional Chinese Medicine,2013,26(07):13.
[7]孙国荣,景克荣,权亚喜.生脉注射液对慢性心衰患者心功能及其心率变异性的影响[J].西部中医药,2013,26(04):68.
　SUN Guorong,JING Kerong,QUAN Yaxi.The Influence of ShengMai Injection on Heart Function and Heart Rate Variability of Patients with Chronic Heart Failure[J].Western Journal of Traditional Chinese Medicine,2013,26(07):68.
[8]俄静,夏小军,杨楠.益气温阳法治疗慢性血小板减少性紫癜经验举隅[J].西部中医药,2013,26(06):58.
　E Jing,XIA Xiaojun,YANG Nan.Invigorating Qi and Yang Method in Treating Chronic Thrombocytopenic Purpura[J].Western Journal of Traditional Chinese Medicine,2013,26(07):58.
[9]马继利.中西药物联用治疗慢性萎缩性胃炎58例[J].西部中医药,2013,26(06):91.
　MA Jili.Treatment for 58 Cases of Chronic Atrophic Gastritis with Integrative Medicines[J].Western Journal of Traditional Chinese Medicine,2013,26(07):91.
[10]王富国,张之舜,丁芬.中西医结合治疗慢性阻塞性肺疾病急性加重期28例疗效观察[J].西部中医药,2012,25(09):70.
　WANG Fu-guo,ZHANG Zhi-shun,DING Fen.Treating 28 Cases of Chronic Obstructive Pulmonary Disease at Acute Exacerbation with Integrated Traditional Chinese and Western Medicine[J].Western Journal of Traditional Chinese Medicine,2012,25(07):70.
[11]延保国.还原型谷胱甘肽联合苦黄注射液治疗慢性乙型肝炎40例疗效观察[J].西部中医药,2012,25(09):68.
　YAN Bao-guo.Curative Observation on Reduced Glutathione for Injection and KuHuang Injection in Treating 40 Cases of Chronic Hepatitis B[J].Western Journal of Traditional Chinese Medicine,2012,25(07):68.
[12]于晨媛.茵陈蒿汤加味联合西药治疗慢性丙型肝炎65例[J].西部中医药,2013,26(09):82.
　YU Chenyuan.Modified YinChenHao Tang Combined with Western Medicine for 65 Cases of Chronic Hepatitis C[J].Western Journal of Traditional Chinese Medicine,2013,26(07):82.
[13]何晶,袁征,陆原,等.基于数据挖掘探讨周珉教授治疗慢性乙型肝炎的用药规律及经验[J].西部中医药,2021,34(06):81.[doi:10.12174/j.issn.2096-9600.2021.06.19]
　HE Jing,YUAN Zheng,LU Yuan,et al.Professor Zhou Min′s Medication Rules and Experience of Treating Chronic Hepatitis B Based on Data Mining[J].Western Journal of Traditional Chinese Medicine,2021,34(07):81.[doi:10.12174/j.issn.2096-9600.2021.06.19]
[14]陈泽山,朱文琳,陈柏尧,等.从湿热中阻论治慢性乙型肝炎研究进展[J].西部中医药,2023,36(02):133.[doi:10.12174/j.issn.2096-9600.2023.02.31]
　CHEN Zeshan,ZHU Wenlin,CHEN Baiyao,et al.Research Progress of Treatment of Chronic Hepatitis B from Damp-heat Obstructing the Middle Energizer[J].Western Journal of Traditional Chinese Medicine,2023,36(07):133.[doi:10.12174/j.issn.2096-9600.2023.02.31]
[15]蒙荫杰,邱华,黄鹏,等.白花香莲解毒颗粒治疗HBeAg阳性慢性乙型肝炎的临床疗效及对血浆外泌体miR-122表达的影响[J].西部中医药,2023,36(06):110.[doi:10.12174/j.issn.2096-9600.2023.06.26]
　MENG Yinjie,QIU Hua,HUANG Peng,et al.Clinical Effects of Baihua Xianglian Detoxification Granules in the Treatment of Positive HBeAg Chronic Hepatitis B and Its Influence on Plasma Exosomal miR-122 Expressions[J].Western Journal of Traditional Chinese Medicine,2023,36(07):110.[doi:10.12174/j.issn.2096-9600.2023.06.26]
[16]李彦波,吕文良,强睿,等.吕文良教授“火候”学理论治疗慢性乙型病毒性肝炎[J].西部中医药,2024,37(04):42.[doi:10.12174/j.issn.2096-9600.2024.04.09]
　LI Yanbo,LYU Wenliang,QIANG Rui,et al.Professor Lyu Wenliang′s "Fire" Theory in the Treatment of Chronic Viral Hepatitis B[J].Western Journal of Traditional Chinese Medicine,2024,37(07):42.[doi:10.12174/j.issn.2096-9600.2024.04.09]

备注/Memo

备注/Memo:
收稿日期：2012-03-26 *项目基金：上海市卫生局综合医院重点优势特色专病(慢性重型肝炎)建设项目(2008YSZB007) 作者简介：叶佩燕(1971—)，女，副主任医师。研究方向：急慢性肝胆疾病的中西医结合诊治。 △通讯作者：陈晓蓉(1964—)，女，硕士研究生导师，主任医师。研究方向：急慢性肝胆疾病的中西医结合诊治。
更新日期/Last Update: 2012-07-15