[1]吴小秦,王翔,符国庆,等.温肺健脾方治疗肺脾虚寒型变应性鼻炎91例[J].西部中医药,2021,34(12):84-87.[doi:10.12174/j.issn.2096-9600.2021.12.22]
　WU Xiaoqin,WANG Xiang,FU Guoqing,et al.Lung-warming Spleen-invigorating Prescription in Treating 91 Patients with Allergic Rhinitis of Lung and Spleen Deficiency-cold Pattern[J].Western Journal of Traditional Chinese Medicine,2021,34(12):84-87.[doi:10.12174/j.issn.2096-9600.2021.12.22]
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温肺健脾方治疗肺脾虚寒型变应性鼻炎91例
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
34
期数:
2021年12期
页码:
84-87
栏目:
临证经验
出版日期:
2021-12-15

文章信息/Info

Title:
Lung-warming Spleen-invigorating Prescription in Treating 91 Patients with Allergic Rhinitis of Lung and Spleen Deficiency-cold Pattern
作者:
吴小秦;  王翔;  符国庆;  李淑芳;  吴怡莎;  谭业农
海南省中医院，海南 海口 570203
Author(s):
WU Xiaoqin;  WANG Xiang;  FU Guoqing;  LI Shufang;  WU Yisha;  TAN Yenong
Hainan Provincial Hospital of Traditional Chinese Medicine, Haikou 570203, China
关键词:
变应性鼻炎; 肺脾虚寒证; 温肺健脾方; 临床疗效; 生活质量; 复发率
Keywords:
allergic rhinitis; lung spleen deficiency cold pattern; lung-warming spleen-invigorating prescription; clinical effects; quality of life; the relapse rate
分类号:
R765.21
DOI:
10.12174/j.issn.2096-9600.2021.12.22
文献标志码:
B
摘要:
目的观察温肺健脾方治疗肺脾虚寒型变应性鼻炎的临床疗效。 方法选择182例肺脾虚寒型变应性鼻炎患者，采用随机双盲法分为观察组和对照组，每组91例。对照组给予西替利嗪、布地奈德鼻喷雾剂治疗，观察组在对照组治疗基础上给予温肺健脾方治疗，比较两组治疗后临床疗效，生活质量、证候评分，实验室检查指标［鼻腔分泌物嗜酸粒细胞（eosinophil，EOS）、P物质（substance P，SP）］水平，不良反应发生率及复发率。 结果观察组总有效率［91.21%（83/91）］明显高于对照组［72.53%（66/91）］（P＜0.05）。观察组在生理功能、生理职能、总体健康、活力、社会功能、精神健康各维度的得分明显高于对照组（P＜0.05），在躯体疼痛、情感角色限制维度得分与对照组比较，差异无统计学意义（P＞0.05）。治疗后，两组证候积分、EOS百分比、SP水平均明显低于治疗前（P＜0.05），且观察组上述指标明显低于对照组（P＜0.05）。观察组治疗后不良反应发生率及复发率均低于对照组（P＜0.05）。 结论温肺健脾方治疗肺脾虚寒型变应性鼻炎近期疗效显著，不仅能调节免疫功能及炎性状态，而且可降低复发率，提高预后生活质量水平，具有良好的安全性。
Abstract:
ObjectiveTo observe clinical effects of lung-warming spleen-invigorating prescription in the treatment of allergic rhinitis of lung and spleen deficiency-cold pattern. MethodsAll 182 patients were allocated to the observation group and the control group using random double-blind method, 91 cases in each group. The control group was treated with cetirizine and budesonide nasal spray, and the observation group took lung-warming spleen-invigorating prescription based on the therapy the control group accepted, to compare clinical effects, quality of life, the scores of clinical syndromes, lab inspection indexes (the levels of EOS and SP in nasal secretions), the incidences of adverse reaction and the relapse rate between both groups after treating. ResultsTotal effective rate of the observation group was 91.21% (83/91), notably higher than 72.53% (66/91) of the control group (P<0.05). The observation group was higher than the control group in the scores of physiological function, physiological role, overall health, vitality, social function, and mental health (P>0.05) while the difference had no statistical meaning when the observation group was compared with the control group in the scores of somatic pain, emotional role limitation (P>0.05). After treating, the scores of clinical syndrome, EOS percentage and the levels of SP were lower than these before treating (P<0.05), and the indexes above of the observation group were lower than these of the control group (P<0.05). The incidence of adverse reaction and the relapse rate of the observation group after treating were lower than these of the control group (P<0.05). ConclusionLung-warming spleen-invigorating prescription could gain notable short-term effects in treating allergic rhinitis of lung and spleen deficiency-cold pattern, it could not only regulate immunologic function and inflammatory state of the patients, but also decrease the relapse rate after treating, improve quality of life after the prognosis, and it has good safety.

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[2]卢健敏.温肺止流丹对变应性鼻炎大鼠免疫调节作用机制的研究[J].西部中医药,2013,26(07):26.
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[3]谢强,指导：付文洋.变应性鼻炎中医治疗研究现状[J].西部中医药,2015,28(03):140.
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备注/Memo

备注/Memo:
吴小秦（1984—），男，硕士学位，主治医师。研究方向：耳鼻喉科疾病的中西医结合诊治。海南省医药卫生科研支撑项目（1326360，10A2010）。
更新日期/Last Update: 2021-12-15