[1]李瑞,王宇.黄芪多糖的抗肿瘤作用机制研究进展[J].西部中医药,2022,35(09):150-154.[doi:10.12174/j.issn.2096-9600.2022.09.32]
　LI Rui,WANG Yu.Research Progress of Anti-tumor Mechanism of Astragalus Polysaccharide[J].Western Journal of Traditional Chinese Medicine,2022,35(09):150-154.[doi:10.12174/j.issn.2096-9600.2022.09.32]
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黄芪多糖的抗肿瘤作用机制研究进展
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
35
期数:
2022年09期
页码:
150-154
栏目:
研究进展
出版日期:
2022-09-15

文章信息/Info

Title:
Research Progress of Anti-tumor Mechanism of Astragalus Polysaccharide
作者:
李瑞1, 王宇2
1.陕西中医药大学第二临床医学院, 陕西 咸阳 712046
2.陕西中医药大学医学科研实验中心
Author(s):
LI Rui1, WANG Yu2
1.The Second Clinical Medical School of Shaanxi University of Chinese Medicine, Xianyang 712046, China
2.Medical Research and Experimental Center of Shaanxi University of Chinese Medicine
关键词:
肿瘤; 黄芪多糖; 作用机制; 综述
Keywords:
tumor; astragalus polysaccharide; mechanism; review
分类号:
R285.6
DOI:
10.12174/j.issn.2096-9600.2022.09.32
摘要:
综述近几年黄芪多糖（astragalus polysaccharides，APS）的多种抗肿瘤机制研究进展，指出APS在肺癌、乳腺癌、头颈部肿瘤等肿瘤的增殖、凋亡、生长和转移等致癌过程中起重要作用，而且APS协同化疗药物的疗效优于单纯用药，但其联合机制还有待研究，同时APS的抗癌作用多随浓度和时间的增加而增加，用于临床患者的剂量和时间还有待明确。
Abstract:
Astragalus polysaccharide (APS) has played an important role in the proliferation, apoptosis, growth and metastasis of tumor including lung cancer, breast cancer, head and neck cancer by reviewing research progress on diversified anti-cancer mechanisms of APS in the recent years, and synergistic effects between APS and chemotherapy drugs are superior to these of single use of herbs, however, its combination mechanism needs to be studied, meanwhile, anti-tumor action of APS enhanced with the increase of its concentration and time, the dosage and duration of use in clinical patients remains to be determined.

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备注/Memo

备注/Memo:
李瑞（1997—），女，在读硕士研究生。研究方向：耳鼻喉。国家自然科学基金（81402344）；陕西省自然科学基础研究计划（2015JQ8308）；陕西省青年科技新星项目（2018KJXX-096）；陕西省教育厅科学研究计划（自然科学专项）（16JK1221）。
更新日期/Last Update: 2022-10-08