[1]王亚峰,谢亲建,丁晓煜,等.白刺对胃癌MGC-803细胞的抑制作用[J].西部中医药,2018,31(05):14-17.
　WANG Yafeng,XIE Qinjian,DING Xiaoyu,et al.Study of Inhibitory Action of BaiCi on Gastric Cancer MGC-803 Cells[J].Western Journal of Traditional Chinese Medicine,2018,31(05):14-17.
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白刺对胃癌MGC-803细胞的抑制作用()
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
31
期数:
2018年05期
页码:
14-17
栏目:
出版日期:
2018-05-15

文章信息/Info

Title:
Study of Inhibitory Action of BaiCi on Gastric Cancer MGC-803 Cells
文章编号:
1004-6852(2018)05-0014-04
作者:
王亚峰1，谢亲建2，丁晓煜2，孙晓刚2，罗淑平3，贺葵邦1
1 青海省人民医院药剂科，青海 西宁 810000； 2 武警甘肃省总队医院； 3 中国人民解放军兰州总医院
Author(s):
WANG Yafeng1, XIE Qinjian2, DING Xiaoyu2, SUN Xiaogang2, LUO Shuping3, HE Kuibang1
1 Pharmacy Department, Qinghai Provincial People′s Hospital, Xining 810000, China;2 Gansu Provincial General Hospital of Armed Police Force; 3 Lanzhou General Hospital of the Chinese People′s Liberation Army
关键词:
胃癌; 胃癌细胞株(MGC-803); 白刺; 药理
Keywords:
gastric cancer;  MGC-803 cells;  BaiCi;  pharmacology
分类号:
R735.2
文献标志码:
A
摘要:
目的：探讨白刺对胃癌MGC-803细胞的抑制作用。方法：采用噻唑蓝法(MTT法)检测白刺对胃癌MGC-803细胞的抑制率，荧光显微镜检测白刺对胃癌MGC-803细胞的凋亡效果，通过病理切片观察白刺对胃癌MGC-803细胞的毒性。结果：白刺对胃癌MGC-803细胞具有抑制作用，可使细胞核固缩，出现凋亡小体，病理结果显示白刺对昆明小鼠的脏器没有明显毒性。结论：白刺具有抑制胃癌MGC-803细胞的作用。
Abstract:
Objective: To explore the inhibitory effect of BaiCi (Nitraria schoberi L.) on gastric cancer MGC-803 cells. Methods: The inhibition rate of BaiCi on gastric cancer MGC-803 cells were detected by using MTT method, the apoptosis effects of BaiCi on gastric cancer MGC-803 cells were measured by using fluorescence microscope, the toxicity of BaiCi on gastric cancer MGC-803 cells were observed by pathological section. Results: BaiCi owned the inhibitory action on gastric cancer MGC-803 cells which showed karyopyknosis and apoptotic body, pathological results demonstrated that BaiCi had no obvious toxicity to the viscera of KunMing mice. Conclusion: BaiCi possesses the inhibitory action on gastric cancer MGC-803 cells.

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备注/Memo

备注/Memo:
收稿日期：2017-09-10 作者简介：王亚峰(1981—)，男，硕士学位，副主任药师。研究方向：中药药理学与肿瘤药理学。
更新日期/Last Update: 2018-05-15