[1]周蓉,陈政,刘卢平.《金匮要略》酸枣仁汤合归脾丸治疗亚健康失眠69例[J].西部中医药,2022,35(10):90-93.[doi:10.12174/j.issn.2096-9600.2022.10.18]
　ZHOU Rong,CHEN Zheng,LIU Luping.Treating 69 Cases of Sub-health Insomnia by Suanzaoren Tang and Guipi Pills from Synopsis of Golden Chamber[J].Western Journal of Traditional Chinese Medicine,2022,35(10):90-93.[doi:10.12174/j.issn.2096-9600.2022.10.18]
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《金匮要略》酸枣仁汤合归脾丸治疗亚健康失眠69例
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
35
期数:
2022年10期
页码:
90-93
栏目:
出版日期:
2022-10-15

文章信息/Info

Title:
Treating 69 Cases of Sub-health Insomnia by Suanzaoren Tang and Guipi Pills from Synopsis of Golden Chamber
作者:
周蓉, 陈政, 刘卢平
三峡大学中医医院/宜昌市中医医院,湖北 宜昌 443000
Author(s):
ZHOU Rong, CHEN Zheng, LIU Luping
Three Gorges University Hospital of TCM/Yichang City Hospital of TCM, Yichang 443000, China
关键词:
失眠; 亚健康; 酸枣仁汤; 归脾丸; 临床疗效
Keywords:
insomnia;  sub-health; pills; clinical effects
分类号:
R256.23
DOI:
10.12174/j.issn.2096-9600.2022.10.18
文献标志码:
B
摘要:
目的探究酸枣仁汤合归脾丸对亚健康状态患者失眠的治疗效果及对生活质量的干预作用。 方法选取138例亚健康失眠状态患者作为研究对象，依据随机数字表法将所有患者随机分为对照组64例和观察组65例。对照组给予归脾丸中成药治疗，观察组在对照组的基础上联合应用酸枣仁汤治疗，两组共治疗4周。比较两组临床疗效，治疗前后匹兹堡睡眠质量指数（Pittsburgh sleep quality index，PSQI）、WHO生活质量量表（WHO quality of life scale，WHOQOL-BREF）及爱泼沃斯嗜睡量表（Epworth sleepiness scale，ESS）积分，并进行安全性评价。 结果临床总有效率观察组为［95.38%（62/65）］，对照组为［81.25%（52/64）］，两组比较差异有统计学意义（P＜0.05）。治疗后，两组PSQI评分及ESS积分均较治疗前降低（P＜0.05），且观察组治疗后改善较对照组更显著（P＜0.05）。治疗后，两组生理、心理、环境和社会关系领域评分均较治疗前升高（P＜0.05），观察组心理和社会关系2个维度评分提高较对照组更显著（P＜0.05）。观察组不良反应发生率［7.69%（5/65）］与对照组［7.69%（5/65）］比较，差异无统计学意义（P＞0.05）。 结论酸枣仁汤合归脾丸治疗亚健康状态患者失眠疗效确切，且效果优于单方治疗，安全可靠。
Abstract:
ObjectiveTo investigate clinical effects of Suanzaoren Tang and Guipi pills in the treatment of insomnia in sub-health patients and its intervention for quality of life. MethodsA total of 138 patients were chosen as the object of the study, and they were allocated into 64 cases in the control group and 65 cases in the observation group according to random number table method. The control group was treated by Chinese patent medicine Guipi pills, and the observation group by Suanzaoren Tang based on the therapy the control group accepted, and both groups were treated for four weeks. To compare clinical effects between both groups, PSQI, WHOQOL-BREF and ESS scales before and after treatment, and conduct safety assessment. ResultsOverall effective rate of the observation group was [95.38%(62/65)], higher than [81.25% (52/64)] of the control group, and the difference had statistical meaning (P<0.05). After the treatment, PSQI and ESS scores of both groups were lower than these before the treatment (P<0.05), and the improvement of the observation group was more significant than that of the control group (P<0.05). After treating, the scores in physical, psychological, environmental and social relation were increased than these before the treatment (P<0.05), the increase in the scales of psychological and social relationship was more notable than that in the control group (P<0.05). The difference had no statistical meaning in the incidence of the adverse reaction between the observation group [7.69% (5/65)] and the control group [7.69% (5/65)](P>0.05). ConclusionSuanzaoren Tang and Guipi pills could obtain definite effects in the treatment of insomnia in sub-health patients, its effects are superior to these of single prescription, and they are safe and reliable.

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备注/Memo

备注/Memo:
周蓉（1981—），女，副主任医师。研究方向：基于治未病理论治疗各种疲劳、失眠、便秘等亚健康状态。
更新日期/Last Update: 2022-10-15