[1]郭斯一,王世钦,吕志达,等.调气养神汤加味治疗瘀血内阻型冠心病心绞痛失眠症临床观察[J].西部中医药,2026,39(02):141-144.[doi:10.12174/j.issn.2096-9600.2026.02.27]
　GUO Siyi,WANG Shiqin,LYU Zhida,et al.Clinical Observation on Modified Qi-regulating and Spirit-nourshing Decoction in the Treatment of Blood Stasis Obstructing the Interior Type of Stable Angina Pectoris in Coronary Heart Disease and Insomnia[J].Western Journal of Traditional Chinese Medicine,2026,39(02):141-144.[doi:10.12174/j.issn.2096-9600.2026.02.27]
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调气养神汤加味治疗瘀血内阻型冠心病心绞痛失眠症临床观察()

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
39
期数:
2026年02期
页码:
141-144
栏目:
临床研究
出版日期:
2026-02-15

文章信息/Info

Title:
Clinical Observation on Modified Qi-regulating and Spirit-nourshing Decoction in the Treatment of Blood Stasis Obstructing the Interior Type of Stable Angina Pectoris in Coronary Heart Disease and Insomnia
作者:
郭斯一1, 王世钦2, 吕志达2, 李长达2
1.山东中医药大学，山东 济南 250014
2.淄博市中医医院，山东 淄博 255300
Author(s):
GUO Siyi1, WANG Shiqin2, LYU Zhida2, LI Changda2
1.Shandong University of Traditional Chinese Medicine, Jinan 250014, China
2.Zibo Hospital of TCM, Zibo 255300, China
关键词:
心绞痛; 失眠症; 心电图; 瘀血内阻证; 调气养神汤; 艾司唑仑片
Keywords:
angina pectoris; insomnia; electrocardiogram; blood stasis obstructing the interior type; -regulating and spirit-nourishing decoction; estazolam tablets
分类号:
R259
DOI:
10.12174/j.issn.2096-9600.2026.02.27
文献标志码:
B
摘要:
目的观察调气养神汤加味联合艾司唑仑片治疗瘀血内阻型冠心病稳定型心绞痛（stable angina pectoris，SAP）失眠症的疗效。 方法选取66例老年SAP伴失眠症患者，按随机数字表法分为对照组和治疗组，每组33例。对照组予艾司唑仑片治疗，治疗组在对照组基础上予调气养神汤加味治疗，两组均连续治疗4周。比较两组患者匹兹堡睡眠质量指数（pittsburgh sleep quality index，PSQI）评分、中医证候评分、心电图疗效及失眠疗效。 结果治疗2、4周后，两组患者PSQI评分均降低（P＜0.05），且同时间点治疗组降低更明显（P＜0.05）。治疗4周后，两组患者中医证候评分的各单项症状评分均降低（P＜0.05），且治疗组降低更明显（P＜0.05）；心电图总有效率治疗组［96.97%（32/33）］高于对照组［75.76%（25/33）］（P＜0.05）；失眠改善总有效率治疗组［93.94%（31/33）］高于对照组［69.70%（23/33）］（P＜0.05）。 结论调气养神汤加味联合艾司唑仑片治疗老年瘀血内阻型SAP伴失眠症疗效确切，有助于减轻患者临床症状与中医证候。
Abstract:
ObjectiveTo observe clinical effects of modified Qi-regulating and spirit-nourishing decoction and estazolam tablets in the treatment of blood stasis obstructing the interior type of stable angina pectoris (SAP) in coronary heart disease (CHD) and insomnia. MethodsA total of 66 elderly patients suffering from SAP and insomnia were chosen, and randomized to the control group and the treatment group using random number table method with 33 cases in each. The control group was treated with estazolam tablets, and the treatment group received modified Qi-regulating and spirit-nourishing decoction on the foundation of the therapy of the control group, and both groups were treated for four weeks continuously. To compare PSQI scores, TCM syndrome scores, clinical effects of ECG and insomnia between the two groups. ResultsAfter two and four weeks, PSQI scores were lowered in the two groups (P<0.05), and the decrease in the treatment group was more evident at the same time point (P<0.05). After four weeks of the treatment, the scales of single symptoms of TCM syndrome scores were reduced in the two groups (P<0.05), and the decrease of the treatment group was more evident (P<0.05); overall response rate based on ECG improvement of the treatment group was [96.97%(32/33)], higher than [75.76%(25/33)] of the control group (P<0.05); overall response rate for insomnia improvement of the treatment group reached [93.94%(31/33)], higher than [69.70%(23/33)] of the control group (P<0.05). ConclusionModified Qi-regulating and spirit-nourishing decoction and estazolam tablets demonstrate definite clinical effects in the treatment of blood stasis obstructing the interior type of SAP and insomnia, which is conducive to the reduction of both patients’ clinical symptoms and TCM syndrome scores.

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备注/Memo

备注/Memo:
山东省中医药科技项目（B-2022014）；淄博市医药卫生科研项目（20231502100）。郭斯一（1999—），男，硕士学位，医师。研究方向：中医药治疗心系病。
更新日期/Last Update: 2026-02-15