[1]杨玉华,罗国安,黄 维.浓缩当归丸指纹图谱研究[J].西部中医药,2017,30(11):47-51.
　YANG Yuhua,LUO Guoan,HUANG Wei.Study of the Fingerprint of Concentrated DangGui Pills[J].Western Journal of Traditional Chinese Medicine,2017,30(11):47-51.
点击复制

浓缩当归丸指纹图谱研究()
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
30
期数:
2017年11期
页码:
47-51
栏目:
出版日期:
2017-11-15

文章信息/Info

Title:
Study of the Fingerprint of Concentrated DangGui Pills
文章编号:
1004-6852(2017)11-0047-05
作者:
杨玉华1，罗国安2，黄 维1
1 兰州佛慈制药股份有限公司，甘肃 兰州 730000； 2 清华大学化学系
Author(s):
YANG Yuhua1, LUO Guoan2, HUANG Wei1
1 Lanzhou Foci Pharmaceutical Co., LTD, Lanzhou 730000, China; 2 Department of Chemistry, Tsinghua University
关键词:
浓缩当归丸; 指纹图谱; 多指标控制
Keywords:
concentrated DangGui pills;  fingerprint;  multi-index control
分类号:
R282
摘要:
目的：建立浓缩当归丸高效液相色谱指纹图谱。方法：使用C18(250 mm×4.6 mm，5 μm)反相色谱柱，以乙腈-水(水中含体积比为0.1%的甲酸)为流动相，梯度洗脱，流速1.0 mL/min，检测波长为280 nm。结果：精密度、重现性、稳定性实验中的共有峰相对峰面积、相对保留时间的RSD均小于5%。结论：该方法简便、实用、可靠，可作为评价浓缩当归丸的质量控制指标之一。
Abstract:
Objective: To establish HPLC fingerprint of concentrated DangGui pills. Methods: Reversed-phase C18 chromatographic column (250 mm×4.6 mm, 5 μm) was used by taking acetonitrile-water (water containing methanoic acid in the volume ratio of 0.1%) as mobile phase in the mode of gradient elution, flow velocity was 1.0 mL/min and detection wavelength was 280nm. Results: RSD of relative peak area of common peak and relative retention time(RRT) in the tests of precision, repeatability and stability were all less than 5%. Conclusion: The method, simple and convenient, practical and reliable, could be used as one of the indexes of assessing qualitycontrol for concentrated DangGui pills.

相似文献/References:

[1]鱼光强,高晔珩△.强力感冒片指纹图谱的初步研究[J].西部中医药,2015,28(01):23.
[2]刘君,张丽艳.蚂蟥药材的指纹图谱研究[J].西部中医药,2015,28(10):40.
[3]杨树声.连翘HPLC指纹图谱的建立及其化学模式识别研究[J].西部中医药,2011,24(11):8.
[4]成 瑞,鞠爱华△,白万富,等.蒙药牛胆粉反相高效液相色谱指纹图谱研究*[J].西部中医药,2014,27(02):25.
　CHENG Rui,JU Aihua,BAI Wanfu,et al.Study on Fingerprint of Mongolian Medicine NiuDanFen by RP-HPLC[J].Western Journal of Traditional Chinese Medicine,2014,27(11):25.
[5]刘效栓,张小华,陈二林,等.伤科洁肤液指纹图谱研究*[J].西部中医药,2013,26(12):23.
　LIU Xiaoshuan,ZHANG Xiaohua,CHEN Erlin,et al.Research on Fingerprint of ShangKe JieFu Lotion by HPLC[J].Western Journal of Traditional Chinese Medicine,2013,26(11):23.
[6]王文鹏,冯玉康,郝鹏彬△,等.甘草提取物HPLC指纹图谱及质量评价研究[J].西部中医药,2017,30(11):52.
　WANG Wenpeng,FENG Yukang,HAO Pengbin,et al.Study on HPLC Fingerprint and Quality Evaluation of Licorice Extract[J].Western Journal of Traditional Chinese Medicine,2017,30(11):52.
[7]白婧,肖会敏△,何悦,等.沙菊茶HPLC指纹图谱及7个成分溶出度的研究[J].西部中医药,2018,31(11):26.
　BAI Jing,XIAO Huimin,HE Yue,et al.Study on HPLC Fingerprint and Dissolution Rate of Seven Kinds of Ingredients of ShaJu Tea[J].Western Journal of Traditional Chinese Medicine,2018,31(11):26.
[8]郭敏,展锐,王红丽△.射干扶正口服液指纹图谱研究[J].西部中医药,2019,32(02):41.
　GUO Min,ZHAN Rui,WANG Hongli.Study on Fingerprint of SheGan FuZheng Oral Liquid[J].Western Journal of Traditional Chinese Medicine,2019,32(11):41.
[9]李运,邱国玉△,石晓峰,等.关黄柏饮片标准汤剂的质量标准研究[J].西部中医药,2019,32(07):43.
　LI Yun,QIU Guoyu,SHI Xiaofeng,et al.Quality Standard of Guanhuangbo Standard Decoction[J].Western Journal of Traditional Chinese Medicine,2019,32(11):43.
[10]张平,李冬华,王晓琳,等.不同产地及加工方法对党参饮片质量的影响[J].西部中医药,2019,32(08):20.
　ZHANG Ping,LI Donghua,WANG Xiaolin,et al.Effects of Different Processing Methods and Different Producing Areas on the Quality of Dangshen Decoction Pieces[J].Western Journal of Traditional Chinese Medicine,2019,32(11):20.

备注/Memo

备注/Memo:
收稿日期：2017-02-27 *基金项目：国家科技重大专项子课题(编号2012ZX09101231)。 作者简介：杨玉华(1966—)，女，正高级工程师。研究方向：新药研究与注册。
更新日期/Last Update: 2017-11-15