[1]王思霖,孙志广.参苓白术散加减治疗功能性消化不良临床疗效Meta分析[J].西部中医药,2024,37(08):59-62.[doi:10.12174/j.issn.2096-9600.2024.08.15]
　WANG Silin,SUN Zhiguang.Clinical Effects of Modified Shenling Baizhu Powder in the Treatment of Functional Dyspepsia: A Meta-analysis[J].Western Journal of Traditional Chinese Medicine,2024,37(08):59-62.[doi:10.12174/j.issn.2096-9600.2024.08.15]
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参苓白术散加减治疗功能性消化不良临床疗效Meta分析
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
37
期数:
2024年08期
页码:
59-62
栏目:
二次研究
出版日期:
2024-08-15

文章信息/Info

Title:
Clinical Effects of Modified Shenling Baizhu Powder in the Treatment of Functional Dyspepsia: A Meta-analysis
作者:
王思霖1, 孙志广2
1.南京中医药大学第二附属医院，江苏 南京 210017
2.南京中医药大学，江苏 南京 210023
Author(s):
WANG Silin1, SUN Zhiguang2
1.Second Affiliated Hospital of Nanjing University of Chinese Medicine, Nanjing 210017, China
2.Nanjing University of Chinese Medicine, Nanjing 210023, China
关键词:
消化不良; 功能性; 参苓白术散; 临床疗效; Meta分析
Keywords:
dyspepsia;  functional; powder; clinical efficacy; Meta analysis
分类号:
R256.3
DOI:
10.12174/j.issn.2096-9600.2024.08.15
文献标志码:
A
摘要:
目的评价参苓白术散加减治疗功能性消化不良（functional dyspepsia，FD）的临床疗效。 方法通过知网、万方、维普、PubMed、Web of Science进行文献检索。检索近10年的文献，检索日期为2011年1月1日至2021年4月8日，纳入参苓白术散加减治疗FD的随机对照试验。对纳入的文献进行偏倚风险评估，总有效率和症状总积分使用Review Manager 5.3软件进行Meta分析。 结果共纳入9篇随机对照试验，1005例患者。Meta分析结果：参苓白术散加减治疗FD的总有效率优于对照组（OR=3.78，95%CI：2.53～5.65，Z=6.48，P＜0.01）；症状总积分也优于对照组（MD=-4.57，95%CI：-5.19～-3.95，Z=14.49，P＜0.01）。 结论参苓白术散加减能够改善患者FD的临床症状，具有更好的临床疗效，但纳入的文献数量有限，仍需大样本、高质量、更严格的随机对照试验进一步验证。
Abstract:
ObjectiveTo evaluate the clinical efficacy of modified Shenling Baizhu powder in the treatment of functional dyspepsia (FD). MethodsThe literature on randomized controlled trials (RCTs) of treating FD with modified Shenling Baizhu powder was included and searched from CNKI, Wanfang, VIP, PubMed and Web of Science from January 1st, 2011 to April 8, 2021. The risk of bias in the included literature was assessed, Meta analysis was performed using Review Manager 5.3 software for total effective rate and total symptoms scores. ResultsThe study has included nine RCTs and 1005 patients. Meta analysis results showed that total effec-tive rate of modified Shenling Baizhu powder in the treatment of FD was better than that of the control group (OR=3.78, 95%CI:2.53～5.65, Z=6.48, P<0.01); total symptoms scores were higher than these of the control group(MD=-4.57, 95%CI:-5.19～-3.95, Z=14.49, P<0.01). ConclusionModified Shenling Baizhu powder could improve clinical symptoms in FD patients with better clinical effects, but, large-sample, high-quality, more rigorous randomized controlled trials are still needed for further validation as the number of included literature is limited.

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备注/Memo

备注/Memo:
王思霖（1996—），男，硕士学位，医师。研究方向：消化系统疾病的中西医结合诊治。国家自然科学基金（82074312）。
更新日期/Last Update: 2024-08-15