[1]班志勇,韦桂莲,黄谢梅.银杏达莫注射液抗慢性胰腺炎纤维化的作用[J].西部中医药,2015,28(02):105-107.
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银杏达莫注射液抗慢性胰腺炎纤维化的作用
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
28
期数:
2015年02期
页码:
105-107
栏目:
出版日期:
2015-02-15

文章信息/Info

文章编号:
1004-6852(2015)02-0105-03
作者:
班志勇韦桂莲黄谢梅
河池市人民医院,广西 河池 547000
关键词:
胰腺炎慢性银杏达莫TGF-β1高凝状态
分类号:
R259
摘要:
目的:探讨外周血转化生长因子(TGF-β1)浓度及高凝状态与慢性胰腺炎(CP)纤维化的关系,同时研究银杏达莫注射液对抗慢性胰腺炎纤维化的作用。方法:将50例CP患者随机分为观察组、对照组各25例。2组均给予戒烟、低脂高蛋白饮食、避免饱食等常规治疗,观察组同时予银杏达莫注射液静脉滴注,1次/d。2组连续治疗2周,观察2组治疗前后TGF-β1、凝血及血脂、血液流变学等指标的变化情况。结果:外周血TGF-β1浓度、生化指标、凝血指标、血液流变学指标2组治疗后均明显改善(P<0.05),观察组改善更明显(P<0.05)。结论:外周血TGF-β1与CP纤维化相关,银杏达莫能够抑制外周血TGF-β1表达,同时能改善CP患者血液高凝状态,有利于改善慢性胰腺炎纤维化进展。

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备注/Memo

备注/Memo:
作者简介:班志勇(1972—),男,主治医师。研究方向:内科疾病的中西医结合治疗。
更新日期/Last Update: 2015-02-15