[1]廖挺,刘则鹏,张丽娜.廖志峰应用健脾补肾活血汤治疗慢性再生障碍性贫血临床观察[J].西部中医药,2014,27(11):53-55.
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廖志峰应用健脾补肾活血汤治疗慢性再生障碍性贫血临床观察
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《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
27
期数:
2014年11期
页码:
53-55
栏目:
出版日期:
2014-11-15

文章信息/Info

作者:
廖挺1，刘则鹏2，张丽娜2
1 甘肃省中医院，甘肃 兰州 730050； 2 甘肃中医学院
关键词:
再生障碍性贫血; 慢性; T淋巴细胞亚群; 肿瘤坏死因子; 白介素-3; 健脾补肾活血汤
分类号:
R556.5
文献标志码:
A
摘要:
目的：观察健脾补肾活血汤治疗慢性再生障碍性贫血(再障)的临床疗效。方法：将再障患者80例随机分为对照组、治疗组各40例。对照组采用司坦唑醇片联合环孢素A(CsA)治疗，治疗组在对照组基础上加用健脾补肾活血汤治疗，疗程6个月。观察2组患者临床疗效及治疗前后外周血T细胞亚群、外周血象、血清肿瘤坏死因子α(TNF-α)和白介素3(IL-3)的变化情况。结果：治疗组治疗后CD4升高、CD8降低、CD4/CD8升高；TNF-α降低，IL-3升高，与治疗前及对照组比较差异均有统计学意义(P＜0.O5)。结论：健脾补肾活血汤可能通过改善T淋巴细胞亚群的比例，减少TNF-α造血负调控因子及增加IL-3造血正调控因子的释放，解除对骨髓造血的抑制，从而促进造血功能的恢复。

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备注/Memo

备注/Memo:
作者简介：廖挺(1976—)，男，主治医师。研究方向：消化系统疾病的中医诊治。
更新日期/Last Update: 2014-11-15