[1]郭铁,雷励△,程平荣,等.补肾活血片治疗血管性痴呆60例[J].西部中医药,2019,32(06):75-77.
　GUO Tie,LEI Li,CHENG Pingrong,et al.Treatment for 60 Cases of Vascular Dementia by Kidney-invigorating Blood-activating Tablets[J].Western Journal of Traditional Chinese Medicine,2019,32(06):75-77.
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补肾活血片治疗血管性痴呆60例

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
32
期数:
2019年06期
页码:
75-77
栏目:
出版日期:
2019-06-15

文章信息/Info

Title:
Treatment for 60 Cases of Vascular Dementia by Kidney-invigorating Blood-activating Tablets
文章编号:
1004-6852(2019)06-0075-03
作者:
郭铁，雷励△，程平荣，陈焱彬
重庆市北碚区中医院脑病一科，重庆 400700
Author(s):
GUO Tie, LEI Li△, CHENG Pingrong, CHEN Yanbin
The First Department of Encephalopathy, Beibei TCM Hospital, Chongqing 400700, China
关键词:
血管性痴呆; 补肾活血片; 认知功能; 生活质量
Keywords:
vascular dementia;  kidney-invigorating blood-activating tablets;  cognitive function;  quality of life
分类号:
R255.2
文献标志码:
B
摘要:
目的：观察补肾活血片治疗血管性痴呆的临床疗效。方法：将120例患者随机分为观察组和对照组，每组60例。2组均给予血管性痴呆患者常规疗法治疗。对照组同时服用胞磷胆碱片，0.2 g/次，3次/d；观察组同时服用补肾活血片，4片/次，3次/d，比较临床疗效，并利用长谷川痴呆量表(HDS)、日常生活能力量表(ADL)和简易精神状况评价量表(MMSE)比较2组患者的HDS、ADL和MMSE评分。结果：总有效率观察组为93.33%，对照组为73.33%，2组比较差异有统计学意义(P＜0.05)。不良反应发生率观察组为3.33%，对照组为8.33%，2组比较差异有统计学意义(P＜0.05)。HDS及ADL评分治疗前后2组组内比较，差异有统计学意义(P＜0.05)；治疗后组间比较差异也有统计学意义(P＜0.05)。MMSE评分治疗后2组比较，差异有统计学意义(P＜0.05)。结论：补肾活血片可有效提高血管性痴呆患者的临床治疗效果，改善患者HDS、ADL和MMSE评分。
Abstract:
Objective: To observe clinical effects of kidney-invigorating blood-activating tablets in treating vascular dementia (VD). Methods: All 120 patients were allocated to two groups, both groups accepted conventional therapy of VD, the control group took citicoline tablets simultaneously, three times each day, 0.2 g each time; the observation group were given kidney-invigorating blood-activating tablets four pills each time, three times each day. To compare clinical effects, HDS scores, ADL and MMSE scores between both groups. Results: Total effective rate of the observation group was 93.33%, higher than 73.33% of the control group, and the difference showed statistical meaning (P＜0.05). The incidence of adverse reaction in the observation group was 3.33%, lower than 8.33% of the control group, and the difference was statistically significant (P＜0.05). The difference was statistically significant in the comparisons of HDS and ADL scores within two groups before and after treating (P＜0.05); the difference could be found between both groups after treating (P＜0.05). The difference was statistically significant in MMSE scores between both groups after treating (P＜0.05). Conclusion: Kidney-invigorating blood-activating tablets could raise therapeutic effects of VD patients, improve HDS, ADL and MMSE scores.

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备注/Memo

备注/Memo:
收稿日期：2018-10-21*基金项目：重庆市卫生局课题资助项目(编号2012-2-51)。作者简介：郭铁(1980—)，男，副主任医师。研究方向：中医脑病的临床诊治。△通讯作者：雷励(1970—)，女，主任医师。研究方向：中医脑病的临床诊治。
更新日期/Last Update: 2019-06-15