[1]尹加亮,童佳兵.中药配方颗粒治疗痰热阻肺型慢性阻塞性肺疾病急性加重期患者的有效性和安全性[J].西部中医药,2021,34(06):89-91.[doi:10.12174/j.issn.2096-9600.2021.06.21]
　YIN Jialiang,TONG Jiabing.Evaluation of the Safety and Effectiveness of Herbal Granules in the Treatment of Acute Exacerbation of COPD of Phlegm-heat Obstracting Lung Pattern[J].Western Journal of Traditional Chinese Medicine,2021,34(06):89-91.[doi:10.12174/j.issn.2096-9600.2021.06.21]
点击复制

中药配方颗粒治疗痰热阻肺型慢性阻塞性肺疾病急性加重期患者的有效性和安全性
分享到：

《西部中医药》[ISSN:2096-9600/CN:62-1204/R]

卷:
34
期数:
2021年06期
页码:
89-91
栏目:
出版日期:
2021-06-15

文章信息/Info

Title:
Evaluation of the Safety and Effectiveness of Herbal Granules in the Treatment of Acute Exacerbation of COPD of Phlegm-heat Obstracting Lung Pattern
作者:
尹加亮1, 童佳兵2
1.六安市第二人民医院，安徽 六安 237008
2.安徽中医药大学第一附属医院
Author(s):
YIN Jialiang1, TONG Jiabing2
1.The Second People′s Hospital of Lu′an City, Lu′an 237008, China
2.The First Affiliated Hospital of Anhui University of Chinese Medicine
关键词:
阻塞性肺疾病; 慢性; 痰热阻肺; 中药配方颗粒; 急性加重期
Keywords:
COPD; phlegm-heat obstructing lung; herbal granules; acute exacerbation
分类号:
R563
DOI:
10.12174/j.issn.2096-9600.2021.06.21
摘要:
目的观察中药配方颗粒剂治疗慢性阻塞性肺疾病（chronic obstructive pulmonary disease，COPD）急性加重期的临床疗效。 方法将80例COPD急性加重期患者随机分为观察组和对照组，每组40例。两组中药处方均为清气化痰丸合贝母瓜蒌散加减，观察组给予中药配方颗粒剂+西医基础治疗，对照组给予中药饮片+西医基础治疗。比较两组中医临床症状积分、生存质量评分、呼吸困难评分、炎性生化指标及临床疗效。 结果同组治疗前后中医临床症状积分、生存质量评分、呼吸困难评分、炎性生化指标比较，差异有统计学意义（P＜0.05）；治疗后上述指标及临床疗效两组间比较差异无统计学意义（P＞0.05）。 结论两种不同中药剂型均能改善COPD急性加重期的临床症状，减低炎性指标水平，提高临床疗效。
Abstract:
ObjectiveTo observe clinical effects of herbal granules in treating acute exacerbation of COPD. MethodsEighty COPD patients were randomized into the observation group and the control group, 40 cases each group. Herbal prescription adopted modified Qingqi Huatan pills and Beimu Gualou powder, the observation group was treated by herbal granules and basic therapy of Western medicine, and the control group herbal decoction pieces and basic therapy of Western medicine. To compare TCM clinical symptoms scores, the scores of quality of life, dyspnea score, inflammatory biochemical indexes and clinical effects between both groups. ResultsThe difference had statistical meaning in TCM clinical symptoms scores, the scores of quality of life, dyspnea score and inflammatory biochemical indexes before and after treating within the same group (P<0.05); the difference had no statistical meaning in the comparisons of these above indexes and clinical effects after treating between both groups (P>0.05). ConclusionTwo kinds of herbal preparations could improve clinical symptoms of AECOPD, lower the levels of inflammatory indexes and raise clinical effects.

相似文献/References:

[1]崔毅.益气活血汤治疗慢性盆腔炎64例临床观察[J].西部中医药,2012,25(12):75.
　CUI Yi.Clinical Observation on YiQi HuoXueTang and Activating Blood Decoction in Treating 64 Cases of Chronic Pelvic Inflammatory Disease[J].Western Journal of Traditional Chinese Medicine,2012,25(06):75.
[2]樊斗霜.枳实消痞丸(汤)合丹参饮加减治疗慢性萎缩性胃炎32例[J].西部中医药,2013,26(02):72.
　FAN Doushuang.Modified ZhiShi XiaoPiWan(Prescription) and DanShenYin in Treating 32 Cases of Chronic Atrophic Gastritis[J].Western Journal of Traditional Chinese Medicine,2013,26(06):72.
[3]尤海鹰.制萎煎治疗脾胃虚弱型慢性萎缩性胃炎40例[J].西部中医药,2013,26(03):84.
　YOU Haiying.ZhiWeiJian in Treating 40 Cases of Chronic Atrophic Gastritis of Spleen-stomach Deficiency Pattern[J].Western Journal of Traditional Chinese Medicine,2013,26(06):84.
[4]张建平,刘洁,赵志亮.针灸治疗慢性前列腺炎25例疗效观察[J].西部中医药,2013,26(03):111.
　ZHANG Jianping,LIU Jie,ZHAO Zhiliang.Observation on Acupuncture in Treating 25 Cases of Chronic Prostatitis[J].Western Journal of Traditional Chinese Medicine,2013,26(06):111.
[5]魏国俊,郑恒恒,指导：燕中.损伤胶囊与正骨水治疗慢性软组织损伤疗效比较[J].西部中医药,2013,26(11):8.
　WEI Guojun,ZHENG Hengheng,Director: YAN Zhong.The Difference in Clinical Effects between SunShang Capsule and Bonesetting Liquid in Treating Chronic Soft Tissue Injury[J].Western Journal of Traditional Chinese Medicine,2013,26(06):8.
[6]朱建坤,温晓辉,梁玉杰△.敦煌葆元膏对下丘脑-垂体-肾上腺轴作用的实验研究*[J].西部中医药,2013,26(11):13.
　ZHU Jiankun,WEN Xiaohui,LIANG Yujie.Experimental Study on the Effects of DunHuang BaoYuan Ointment on Hypothalamic-pituitary-adrenal Axis[J].Western Journal of Traditional Chinese Medicine,2013,26(06):13.
[7]孙国荣,景克荣,权亚喜.生脉注射液对慢性心衰患者心功能及其心率变异性的影响[J].西部中医药,2013,26(04):68.
　SUN Guorong,JING Kerong,QUAN Yaxi.The Influence of ShengMai Injection on Heart Function and Heart Rate Variability of Patients with Chronic Heart Failure[J].Western Journal of Traditional Chinese Medicine,2013,26(06):68.
[8]俄静,夏小军,杨楠.益气温阳法治疗慢性血小板减少性紫癜经验举隅[J].西部中医药,2013,26(06):58.
　E Jing,XIA Xiaojun,YANG Nan.Invigorating Qi and Yang Method in Treating Chronic Thrombocytopenic Purpura[J].Western Journal of Traditional Chinese Medicine,2013,26(06):58.
[9]马继利.中西药物联用治疗慢性萎缩性胃炎58例[J].西部中医药,2013,26(06):91.
　MA Jili.Treatment for 58 Cases of Chronic Atrophic Gastritis with Integrative Medicines[J].Western Journal of Traditional Chinese Medicine,2013,26(06):91.
[10]延保国.还原型谷胱甘肽联合苦黄注射液治疗慢性乙型肝炎40例疗效观察[J].西部中医药,2012,25(09):68.
　YAN Bao-guo.Curative Observation on Reduced Glutathione for Injection and KuHuang Injection in Treating 40 Cases of Chronic Hepatitis B[J].Western Journal of Traditional Chinese Medicine,2012,25(06):68.
[11]王兰娣,潘文.沙美特罗替卡松联合益气养阴合剂治疗轻症及缓解期COPD36例[J].西部中医药,2012,25(05):76.
　WANG Lan-di,PAN Wen.Treatment for 36 Cases of Chronic Obstructive Pulmonary Disease at Mild and Remission Stages with Salmeterol Fluticasone and Mixture of Replenishing Qi and Nourishing Yin[J].Western Journal of Traditional Chinese Medicine,2012,25(06):76.
[12]许振林,许正龙,贾永兰,等.慢肺饮氧动雾化吸入治疗慢性阻塞性肺疾病137例[J].西部中医药,2013,26(09):5.
　XU Zhenlin,XU Zhenglong,JIA Yonglan,et al.Treatment for 137 Cases of Chronic Obstructive Pulmonary Disease with Oxygen Atomizing Inhalation of ManFei Drink[J].Western Journal of Traditional Chinese Medicine,2013,26(06):5.
[13]李娜,张中新,李双霞.火龙督脉铺灸治疗慢性阻塞性肺疾病稳定期42例[J].西部中医药,2013,26(09):98.
　LI Na,ZHANG Zhongxin,LI Shuangxia.Treating 42 Cases of Chronic Obstructive Pulmonary Disease at Stationary Phase with Fire Dragon Therapy of Long-snake Moxibustion along Governor Meridian[J].Western Journal of Traditional Chinese Medicine,2013,26(06):98.
[14]郑引水,马国义.曲安奈德注射液穴位注射治疗慢性阻塞性肺病急性加重期 35 例[J].西部中医药,2014,27(08):115.
[15]李英梅,刘莉.中医护理对慢性阻塞性肺疾病急性加重期患者的干预效果研究[J].西部中医药,2014,27(10):148.
[16]惠朋利,李英,贺鹏.苏黄止咳胶囊联合噻托溴铵治疗慢性阻塞性肺疾病46例[J].西部中医药,2018,31(12):80.
　HUI Pengli,LI Ying,HE Peng.SuHuang Cough-stopping Capsules and Tiotropium Bromide in Treating 46 Cases of Chronic Obstructive Pulmonary Disease[J].Western Journal of Traditional Chinese Medicine,2018,31(06):80.
[17]陈茜,刘伟,姜华,等.参苓白术散联合氨茶碱片治疗慢性阻塞性肺疾病的临床疗效[J].西部中医药,2020,33(06):95.[doi:10.12174/j.issn.1004-6852.2020.06.25]
　CHEN Xi,LIU Wei,JIANG Hua,et al.A Study on Clinical Effects of Shenling Baizhu Powder Combined with Aminophylline Tablets in Treating COPD[J].Western Journal of Traditional Chinese Medicine,2020,33(06):95.[doi:10.12174/j.issn.1004-6852.2020.06.25]
[18]魏睿,由丽娜,夏杰,等.慢性阻塞性肺疾病中医“寒饮”证患者报告结局量表的信度与效度评价[J].西部中医药,2021,34(02):80.[doi:10.12174/j.issn.2096-9600.2021.02.22]
　WEI Rui,YOU Lina,XIA Jie,et al.Evaluation of Reliability and Validity of CFS-COPD-PRO for COPD patients of "Cold and Fluid" Pattern[J].Western Journal of Traditional Chinese Medicine,2021,34(06):80.[doi:10.12174/j.issn.2096-9600.2021.02.22]
[19]刘海,沈娅妮,刘晓梅,等.五禽戏对稳定期慢性阻塞性肺疾病患者有效性的Meta分析[J].西部中医药,2023,36(02):53.[doi:10.12174/j.issn.2096-9600.2023.02.12]
　LIU Hai,SHEN Yani,LIU Xiaomei,et al.Meta Analysis of the Effectiveness of Wu Qin Xi on Stable COPD Patients[J].Western Journal of Traditional Chinese Medicine,2023,36(06):53.[doi:10.12174/j.issn.2096-9600.2023.02.12]
[20]李莉莎,王凤婵.麻杏石甘汤调控TLR4/NF-κB信号通路治疗慢性阻塞性肺疾病的机制[J].西部中医药,2023,36(04):7.[doi:10.12174/j.issn.2096-9600.2023.04.02]
　LI Lisha,WANG Fengchan.The Mechanism of Maxing Shigan Decoction in the Treatment of Chronic Obstructive Pulmonary Disease by Regulating TLR4/NF-κB Signaling Pathway[J].Western Journal of Traditional Chinese Medicine,2023,36(06):7.[doi:10.12174/j.issn.2096-9600.2023.04.02]

备注/Memo

备注/Memo:
尹加亮（1987—），男，硕士学位，主治医师。研究方向：呼吸系统疾病的中医药防治。2017年安徽省科技重大专项计划项目（17030801009）。
更新日期/Last Update: 2021-06-15